Evidence map›Paper›PMID 32393578›Full record

ArticleThe Journal of biological chemistry2020

The NMDA receptor subunit GluN3A regulates synaptic activity-induced and myocyte enhancer factor 2C (MEF2C)-dependent transcription.

Liang-Fu Chen, Michelle R Lyons, Fang Liu, Matthew V Green, Nathan G Hedrick, Ashley B Williams, Arthy Narayanan, Ryohei Yasuda, Anne E West

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. The GluN3-containing NMDA receptors.Channels (Austin, Tex.) · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. GluN3A and Excitatory Glycine Receptors in the Adult Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Review
  9. TheThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Liang-Fu ChenDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Michelle R LyonsDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Fang LiuDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Matthew V GreenDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Nathan G HedrickDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Ashley B WilliamsDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Arthy NarayananDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
Ryohei YasudaMax Planck Florida Institute for Neuroscience, Jupiter, Florida, USA.
Anne E WestDepartment of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA west@neuro.duke.edu.ORCID 0000-0003-0846-139X
Duke University · USMax Planck Florida Institute for Neuroscience · US

Funding

Mechanisms of Ras Signaling in Single SynapsesR01MH080047 · NIMH · MAX PLANCK FLORIDA CORPORATION · PI YASUDA, RYOHEI · 2007 to 2023
$6.8M
Deciphering Biochemical Networks in Single Dendritic SpinesDP1NS096787 · NINDS · MAX PLANCK FLORIDA CORPORATION · PI YASUDA, RYOHEI · 2015 to 2019
$4.8M
Chromatin Mechanisms of Neuronal MaturationR01NS098804 · NINDS · DUKE UNIVERSITY · PI WEST, ANNE ELIZABETH · 2017 to 2021
$2.2M
NIMH NIH HHS R01 MH080047NINDS NIH HHS DP1 NS096787NINDS NIH HHS R01 NS098804
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Transcription, GeneticAnimalsBrain-Derived Neurotrophic FactorCalciumCell NucleusCytoskeletal ProteinsFemaleHippocampusMaleMEF2 Transcription FactorsMembrane GlycoproteinsNerve Tissue ProteinsNeuronal Plasticityp38 Mitogen-Activated Protein KinasesPhosphorylationRatsactivity regulated cytoskeletal-associated proteinBdnf protein, ratBrain-Derived Neurotrophic FactorCalciumCytoskeletal ProteinsGrin3a protein, ratMEF2C protein, ratMEF2 Transcription FactorsMembrane GlycoproteinsNerve Tissue Proteinsp38 Mitogen-Activated Protein KinasesReceptors, N-Methyl-D-AspartateRNA, Small InterferingTetrodotoxinbrain-derived neurotrophic factor (BDNF)excitation-transcription couplinggene regulationglutamate receptor ionotropic NMDA (GluN)ionotropic glutamate receptorMEF2 transcription factorsmitogen-activated protein kinase (MAPK) signalingneurodevelopmentNMDAR)N‐methyl‐d‐aspartate receptor (NMDA receptorp38 MAPKsynaptic activity

Identifiers

PMID32393578
PMCPMC7307204
OpenAlexW3023105362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.