Evidence map›Paper›PMID 32393525›Full record

ArticleRNA (New York, N.Y.)2020

Repeat RNAs associate with replication forks and post-replicative DNA.

Helene M Gylling, Cristina Gonzalez-Aguilera, Martin A Smith, Dominik C Kaczorowski, Anja Groth, Anders H Lund

Open access · greenAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Sequence and ionic requirements of pUG fold quadruplexes.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Helene M GyllingBiotech Research and Innovation Centre, University of Copenhagen, Copenhagen, 2200, Denmark.
Cristina Gonzalez-AguileraBiotech Research and Innovation Centre, University of Copenhagen, Copenhagen, 2200, Denmark.
Martin A SmithGarvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
Dominik C KaczorowskiGarvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
Anja GrothBiotech Research and Innovation Centre, University of Copenhagen, Copenhagen, 2200, Denmark.
Anders H LundBiotech Research and Innovation Centre, University of Copenhagen, Copenhagen, 2200, Denmark.ORCID 0000-0002-7407-3398
University of Copenhagen · DKGarvan Institute of Medical Research · AU

Funding

European Research Council 281765
6 · The paper itself

Abstract

Noncoding RNA has a proven ability to direct and regulate chromatin modifications by acting as scaffolds between DNA and histone-modifying complexes. However, it is unknown if ncRNA plays any role in DNA replication and epigenome maintenance, including histone eviction and reinstallment of histone modifications after genome duplication. Isolation of nascent chromatin has identified a large number of RNA-binding proteins in addition to unknown components of the replication and epigenetic maintenance machinery. Here, we isolated and characterized long and short RNAs associated with nascent chromatin at active replication forks and track RNA composition during chromatin maturation across the cell cycle. Shortly after fork passage, GA-rich-, alpha- and TElomeric Repeat-containing RNAs (TERRA) are associated with replicated DNA. These repeat containing RNAs arise from loci undergoing replication, suggesting an interaction in

Indexed as

Cell CycleCell Line, TumorChromatinDNADNA ReplicationHeLa CellsHistonesHumansProtein Processing, Post-TranslationalRNAChromatinDNAHistonesRNAchromatinDNA replicationrepeatsRNA

Identifiers

PMID32393525
PMCPMC7430672
OpenAlexW3024804916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.