ArticleBMC infectious diseases2020
The clinical significance of IL-6 s and IL-27 s in Bronchoalveolar lavage fluids from children with mycoplasma pneumoniae pneumonia.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 19 citations in OpenAlex.
- Risk factors and construction of prediction model for plastic bronchitis in children withTranslational pediatrics · 2026Article
- Comparative analysis of infection-associated and non-infection-associated pulmonary embolism in children: a multicenter retrospective cohort study.Frontiers in pediatrics · 2026Article
- Predictive significance of peripheral blood IL-6 and FeNO in pediatricTranslational pediatrics · 2025Article
- Bronchoalveolar lavage cytokine profile and clinical features as risk predictors of plastic bronchitis in children with Mycoplasma pneumoniae pneumonia.Italian journal of pediatrics · 2025Article
- Vitamin D promotes autophagy to inhibit LPS-induced lung injury via targeting cathepsin D.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Correlation of prognostic values of IL-6 and PCT levels with the severity of pneumonia caused byPakistan journal of medical sciences · 2025Article
- Study on the Correlation Between the Expression of NF-Ƙb in the Alveolar Lavage Fluid of Children with Severe Mycoplasma Pneumoniae Pneumonia, Its Clinical Characteristics, and Cellular Immunity.Infection and drug resistance · 2024Article
- Vaccination with Mycoplasma pneumoniae membrane lipoproteins induces IL-17A driven neutrophilia that mediates Vaccine-Enhanced Disease.NPJ vaccines · 2022Article
- [Value of autotaxin in predicting refractoryZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Fucoxanthin, a Marine Carotenoid, SuppressesEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Highly Expressed lncRNA GAS5 in the Serum of Children withContrast media & molecular imaging · 2022Article
- Serum cytokine profiling reveals different immune response patterns during general and severeFrontiers in immunology · 2022Article
- Exhausted and Apoptotic BALF T Cells in Proinflammatory Airway Milieu at Acute Phase of Severe Mycoplasma Pneumoniae Pneumonia in Children.Frontiers in immunology · 2021Article
- Ulinastatin plus biapenem for severe pneumonia in the elderly and its influence on pulmonary function and inflammatory cytokines.American journal of translational research · 2021Article
- Identify clinical factors related to Mycoplasma pneumoniae pneumonia with hypoxia in children.BMC infectious diseases · 2020Article
- The immunogenic involvement of miRNA-492 in mycoplasma pneumoniae infection in pediatric patients.Jornal de pediatriaArticle
- Toosendanin AttenuatesDose-response : a publication of International Hormesis SocietyArticle
- Clinical effect of reduning combined with gamma globulin treatment on symptom improvement serum levels of IL-6, 25-(OH)D and LDH in children with severe mycoplasma pneumonia.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIL-6 was associated with the severity of mycoplasma pneumoniae pneumonia (MPP). But the relationship between IL-27 and MPP was unknown.
methodsNinety-eight patients with MPP < 14 years old were enrolled in this study and divided into groups by severity (mild cases and severe cases), infection types (MP single infection group and MP mixed infection group) and DNA loads (low MP DNA loads group and high MP DNA loads group), respectively. Fifteen children with foreign bodies in bronchus were also enrolled as control. IL-6 s and IL-27 s in bronchoalveolar lavage fluids (BALFs) from these children were measured by ELISA.
resultsThere were significant differences in IL-6 s of BALFs from patients between mild cases and severe cases, MP single infection group and MP mixed infection group, and low MP DNA loads group and high MP DNA loads group, respectively (P < 0.05). Compared with IL-6 s of BALFs from control, IL-6 s in BALFs from the 6 patient groups were significantly higher (P < 0.05). IL-27 s in BALFs from MP mixed infection group were significantly lower than those from MP single infection group and control (P < 0.05) respectively.
conclusionIL-6 was firmly associated with MPP and had potential application in clinical practice while IL-27 was not related to MP infection.
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