Evidence map›Paper›PMID 32392889›Full record

ArticleInternational journal of molecular sciences2020

The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis.

Kevin Adam, Jacqueline Lesperance, Tony Hunter, Peter E Zage

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. LHPP expression in triple-negative breast cancer promotes tumor growth and metastasis by modulating the tumor microenvironment.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Histidine Phosphorylation: Protein Kinases and Phosphatases.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kevin AdamMolecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0003-0007-0634
Jacqueline LesperanceDepartment of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, CA 92093, USA.
Tony HunterMolecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N Torrey Pines Road, La Jolla, CA 92037, USA.ORCID 0000-0002-7691-6993
Peter E ZageDepartment of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, CA 92093, USA.
Salk Institute for Biological Studies · USUniversity of California San Diego · US

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Reuben Shaw · 1985 to 2026
$82.8M
Histidine phosphorylation as a new target for cancer therapyR35CA242443 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI HUNTER, TONY R. · 2019 to 2025
$7.5M
The Invisible Phosphoproteome: New Tools to Study Histidine PhosphorylationR01CA194584 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI HUNTER, TONY R. · 2015 to 2019
$2.2M
NCI NIH HHS P30 CA014195NCI NIH HHS R01 CA194584NCI NIH HHS R35 CA242443NIH HHS 1R01CA194584NIH HHS 1R35CA242443
6 · The paper itself

Abstract

Neuroblastoma is the most common extracranial solid tumor in childhood. Gain of chromosome 17q material is found in >60% of neuroblastoma tumors and is associated with poor patient prognosis. The

Indexed as

Up-RegulationAnimalsCell DifferentiationCell Line, TumorCell MovementChildGene Expression Regulation, NeoplasticHumansMiceNeoplasm TransplantationNeuroblastomaNM23 Nucleoside Diphosphate KinasesPhosphorylationPrognosisSignal TransductionSurvival AnalysisNM23 Nucleoside Diphosphate KinasesNME1 protein, humanNME2 protein, humanhistidinekinaseneuroblastomaNME/NM23/NDPKphosphorylation

Identifiers

PMID32392889
PMCPMC7247550
OpenAlexW3020909581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.