Evidence map›Paper›PMID 32392844›Full record

ArticleInternational journal of molecular sciences2020

Coloured Rice Phenolic Extracts Increase Expression of Genes Associated with Insulin Secretion in Rat Pancreatic Insulinoma β-cells.

Gideon Gatluak Kang, Nidhish Francis, Rodney Hill, Daniel LE Waters, Christopher L Blanchard, Abishek Bommannan Santhakumar

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gideon Gatluak KangAustralian Research Council (ARC) Industrial Transformation Training Centre (ITTC) for Functional Grains, Graham Centre for Agricultural Innovation, Wagga Wagga, NSW 2650, Australia.
Nidhish FrancisAustralian Research Council (ARC) Industrial Transformation Training Centre (ITTC) for Functional Grains, Graham Centre for Agricultural Innovation, Wagga Wagga, NSW 2650, Australia.ORCID 0000-0002-9475-2144
Rodney HillSchool of Biomedical Sciences, Charles Sturt University, NSW 2650, Australia.ORCID 0000-0001-9990-1113
Daniel LE WatersAustralian Research Council (ARC) Industrial Transformation Training Centre (ITTC) for Functional Grains, Graham Centre for Agricultural Innovation, Wagga Wagga, NSW 2650, Australia.
Christopher L BlanchardAustralian Research Council (ARC) Industrial Transformation Training Centre (ITTC) for Functional Grains, Graham Centre for Agricultural Innovation, Wagga Wagga, NSW 2650, Australia.
Abishek Bommannan SanthakumarAustralian Research Council (ARC) Industrial Transformation Training Centre (ITTC) for Functional Grains, Graham Centre for Agricultural Innovation, Wagga Wagga, NSW 2650, Australia.ORCID 0000-0003-1836-5035
Australian Research Council · AUCharles Sturt University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose-induced oxidative stress is associated with the overproduction of reactive oxygen species (ROS), which may dysregulate the expression of genes controlling insulin secretion leading to β-cell dysfunction, a hallmark of type 2 diabetes mellitus (T2DM). This study investigated the impact of coloured rice phenolic extracts (CRPEs) on the expression of key genes associated with β-cell function in pancreatic β-cells (INS-1E). These genes included glucose transporter 2 (

Indexed as

AnimalsCell LineDiabetes Mellitus, Type 2Gene Expression RegulationGenetic MarkersGlucoseGlucose Transporter Type 2Homeodomain ProteinsInsulinInsulin-Secreting CellsModels, BiologicalOryzaPhenolsPlant ExtractsRatsSirtuin 1Genetic MarkersGlucoseGlucose Transporter Type 2Homeodomain ProteinsInsulinpancreatic and duodenal homeobox 1 proteinPhenolsPlant ExtractsSirt1 protein, ratSirtuin 1Slc2a2 protein, ratTrans-Activatorscoloured ricegene expressioninsulin secretionpancreatic β-cells functionpolyphenolstype 2 diabetes

Identifiers

PMID32392844
PMCPMC7246603
OpenAlexW3022514824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.