ArticleInternational journal of molecular sciences2020
Construction of an Electrochemical Receptor Sensor Based on Graphene/Thionine for the Sensitive Determination of β-Lactam Antibiotics Content in Milk.
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 28 citations in OpenAlex.
- A Spore-Based Biosensor-on-Pillar Platform for Detecting ß-Lactam Antibiotics in Milk.Molecules (Basel, Switzerland) · 2026Article
- Electrochemical Biosensors for the Detection of Antibiotics in Milk: Recent Trends and Future Perspectives.Biosensors · 2023Review
- Recent advances in quantum dots-based biosensors for antibiotics detection.Journal of pharmaceutical analysis · 2022Review
- Review
- The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021Article
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Authors and funding
12 authors at 1 institution in 1 country.
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Abstract
In antibiotics, β-lactam is one kind of major concern acknowledged as an unavoidable contaminant in milk. Thus, a facile and sensitive method is essential for rapid β-lactam antibiotics detection. In our work, a specific electrochemical receptor sensor based on the graphene/thionine (GO/TH) composite was established. The mechanism of the electrochemical receptor sensor was a direct competitive inhibition of the binding of horseradish peroxidase-labeled ampicillin (HRP-AMP) to the mutant BlaR-CTD protein by free β-lactam antibiotics. Then, horseradish peroxidase (HRP) catalyzed the hydrolysis of the substrate hydrogen peroxide (H
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