ReviewViruses2020
The Lived Experience of Chronic Hepatitis B: A Broader View of Its Impacts and Why We Need a Cure.
Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Reactivation rates of hepatitis B or C or HIV in patients with psoriasis using biological therapies: a systematic review and meta-analysis.Clinical and experimental medicine · 2023Pooled it
- The unvirtuous cycle of discrimination affecting people with hepatitis B: a multi-country qualitative assessment of key-informant perspectives.International journal for equity in health · 2022Guideline
- Elebsiran and PEG-IFNα for chronic hepatitis B infection: a partially randomized, open-label, phase 2 trial.Nature medicine · 2026Trial
- Exploring the Psychosocial Influences on Hepatitis B and Liver Cancer Disparities.Journal of racial and ethnic health disparities · 2026Article
- The Legal Landscape for People Living with Chronic Hepatitis B in Australia: : A Consensus-Based View of Priority Justiciable Issues from Sector Leaders.Journal of bioethical inquiry · 2026Article
- Longitudinal Patterns of Chronic Hepatitis B Care and Treatment Adherence in Australia: A National Linked Data Cohort Study.Journal of viral hepatitis · 2026Article
- The Silent Burden of Hepatitis B-Related Stigma.Journal of viral hepatitis · 2026Article
- "When the virus ages with the patient": Disease-specific quality of life in individuals with hepatitis B virus infection in Ghana.The Journal of international medical research · 2026Article
- Time for a globally unified chronic HBV terminology?JHEP reports : innovation in hepatology · 2025Review
- Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations.Emerging microbes & infections · 2025Article
- Anxiety and Depression Among Hepatitis B Inpatients in Shenzhen, China: A Cross-Sectional Study.Alpha psychiatry · 2025Article
- Meta-analysis of factors associated with the incidence of comorbid depression and anxiety in patients with chronic hepatitis B.World journal of psychiatry · 2025Article
- Envisioning a Multidisciplinary HBV Cure Research Agenda.Current HIV/AIDS reports · 2025Review
- Patient and public health perspectives to inform expansion of hepatitis B treatment guidelines.The lancet. Gastroenterology & hepatology · 2025Review
- Predictors of health-seeking behavior in patients with chronic liver disease and a comparison of health-seeking based on patient-type.BMC gastroenterology · 2025Article
- A culturally adapted mobile cognitive behavioral therapy for individuals with Hepatitis B on depression, anxiety and stress: A pilot randomized controlled trial.Internet interventions · 2025Article
- Best practices for engaging with affected communities: chronic hepatitis B as a case study.Infectious diseases of poverty · 2025Article
- Awareness of hepatitis C prevention and treatment and high-risk behaviors among the general population in Anhui Province: a cross-sectional study.Frontiers in public health · 2025Article
- HBV-Induced Carcinogenesis: Mechanisms, Correlation With Viral Suppression, and Implications for Treatment.Liver international : official journal of the International Association for the Study of the Liver · 2025Review
- Is health, growth and development impaired in children who are Hepatitis B-exposed but uninfected?PLOS global public health · 2025Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic hepatitis B (CHB) is one of the most widespread liver diseases in the world. It is currently incurable and can lead to liver cirrhosis and cancer. The considerable impacts on society caused by CHB through patient mortality, morbidity, and economic loss are well-recognised in the field. This is, however, a narrow view of the harms, given that people living with CHB can be asymptomatic for the majority of their life-long infection. Of less-appreciated importance are the psychosocial harms, which can continue throughout an affected person's lifetime. Here we review the broad range of these impacts, which include fear and anxiety; financial loss and instability; stigma and discrimination; and rejection by society. Importantly, these directly affect patient diagnosis, management, and treatment. Further, we highlight the roles that the research community can play in taking these factors into account and mitigating them. In particular, the development of a cure for hepatitis B virus infection would alleviate many of the psychosocial impacts of CHB. We conclude that there should be a greater recognition of the full impacts associated with CHB to bring meaningful, effective, and deliverable results to the global community living with hepatitis B.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.