ArticleMolecules (Basel, Switzerland)2020
Nootkatone Inhibits Acute and Chronic Inflammatory Responses in Mice.
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Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
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Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
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- The Utilization Value of Condensate Water from the Drying Process ofMetabolites · 2025Article
- Early treatment with nootkatone prevents pressure overload-induced ventricular remodeling and heart failure.Frontiers in pharmacology · 2025Article
- Nootkatone mitigates LPS-induced acute lung injury by modulating the NF-κB and Nrf2 pathways in mice.Frontiers in veterinary science · 2025Article
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- Astrocytic Nrf2 Mediates the Neuroprotective and Anti-Inflammatory Effects of Nootkatone in an MPTP-Induced Parkinson's Disease Mouse Model.Antioxidants (Basel, Switzerland) · 2023Article
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- Phytochemistry and Pharmacology ofMolecules (Basel, Switzerland) · 2023Review
- Nootkatone Supplementation Attenuates Carbon Tetrachloride Exposure-Induced Nephrotoxicity in Mice.Antioxidants (Basel, Switzerland) · 2023Article
- Nootkatone Supplementation Ameliorates Carbon Tetrachloride-Induced Acute Liver Injury via the Inhibition of Oxidative Stress, NF-κB Pathways, and the Activation of Nrf2/HO-1 Pathway.Antioxidants (Basel, Switzerland) · 2023Article
- Artificial Fusions between P450 BM3 and an Alcohol Dehydrogenase for Efficient (+)-Nootkatone Production.Chembiochem : a European journal of chemical biology · 2022Article
- Alpiniae oxyphylla fructus extract promotes longevity and stress resistance ofFrontiers in pharmacology · 2022Article
- Protective Effects of Nootkatone on Renal Inflammation, Apoptosis, and Fibrosis in a Unilateral Ureteral Obstructive Mouse Model.Nutrients · 2021Article
- Advances on (+)-nootkatone microbial biosynthesis and its related enzymes.Journal of industrial microbiology & biotechnology · 2021Article
- Possible Use of Phytochemicals for Recovery from COVID-19-Induced Anosmia and Ageusia.International journal of molecular sciences · 2021Review
- Benign Synthesis of Fused-thiazoles with Enone-based Natural Products and Drugs for Lead Discovery.New journal of chemistry = Nouveau journal de chimie · 2021Article
- Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-Journal of inflammation research · 2021Article
- Nardosinone Alleviates Parkinson's Disease Symptoms in Mice by Regulating Dopamine D2 Receptor.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Editorial to the Special Issue "Biological and Pharmacological Activity of Plant Natural Compounds".Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 2 countries.
Lindaiane Bezerra Rodrigues DantasDepartamento de Saúde, Centro Universitário Dr. Leão Sampaio-UNILEÃO, Av. Leão Sampaio, 400-Lagoa Seca, Juazeiro do Norte 63040-000, Ceará, Brazil.
Ana Letícia Moreira SilvaDepartamento de Saúde, Centro Universitário Dr. Leão Sampaio-UNILEÃO, Av. Leão Sampaio, 400-Lagoa Seca, Juazeiro do Norte 63040-000, Ceará, Brazil.
Cícero Pedro da Silva JúniorLaboratory of Pharmacology and Molecular Chemistry, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, Ceará, Brazil.
Isabel Sousa AlcântaraLaboratory of Pharmacology and Molecular Chemistry, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, Ceará, Brazil.ORCID 0000-0002-2537-0134
Maria Rayane Correia de OliveiraLaboratory of Pharmacology and Molecular Chemistry, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, Ceará, Brazil.ORCID 0000-0003-2568-0519
Anita Oliveira Brito Pereira Bezerra MartinsLaboratory of Pharmacology and Molecular Chemistry, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, Ceará, Brazil.
Jaime Ribeiro-FilhoGonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador 45500-000, Bahia, Brazil.ORCID 0000-0003-3126-6509
Henrique Douglas Melo CoutinhoMicrobiology and Biology Molecular Laboratory, Department of Chemical Biology, Regional University of Cariri, Crato 63105-000, Ceara, Brazil.ORCID 0000-0002-6634-4207
Fabíolla Rocha Santos PassosGraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe 49100-000, Brazil.
Lucindo José Quintans-JuniorGraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe 49100-000, Brazil.ORCID 0000-0001-5155-938X
Irwin Rose Alencar de MenezesLaboratory of Pharmacology and Molecular Chemistry, Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, Crato 63105-000, Ceará, Brazil.ORCID 0000-0003-1065-9581
Raffaele PezzaniO.U. Endocrinology, Department of Medicine (DIMED), University of Padova, via Ospedale 105, 35128 Padova, Italy.ORCID 0000-0003-3156-2500
Sara VitaliniDepartment of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy.ORCID 0000-0001-7557-9473
Universidade Regional do Cariri · BRCentro Universitário do Norte · BRUniversidade Federal de Sergipe · BRFundação Oswaldo Cruz · BRUniversity of Milan · ITUniversity of Padua · IT
Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico 304291/2017-0
Abstract
Nootkatone (NTK) is a sesquiterpenoid found in essential oils of many species of
Indexed as
Acute-Phase ReactionAnimalsAnti-Inflammatory AgentsCapillary PermeabilityCarrageenanCotton FiberCyclooxygenase 2Disease Models, AnimalEdemaFemaleGranulomaHistamineInflammationInterleukin-1betaLeukocytesMaleAnti-Inflammatory AgentsCarrageenanCyclooxygenase 2HistamineInterleukin-1betanootkatonePeroxidasePolycyclic SesquiterpenesReceptors, HistamineTumor Necrosis Factor-alphaacute inflammationanti-inflammatorygranulomanootkatone
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.