Trial reportNutrients2020
Impact of Intensive Lifestyle Treatment (Diet Plus Exercise) on Endothelial and Vascular Function, Arterial Stiffness and Blood Pressure in Stage 1 Hypertension: Results of the HINTreat Randomized Controlled Trial.
Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- An updated network meta-analysis of non-pharmacological interventions for primary hypertension in adults: insights from recent studies.Systematic reviews · 2024Pooled it
- Arterial stiffness measured by pulse wave velocity correlated with cognitive decline in hypertensive individuals: a systematic review.BMC neurology · 2024Pooled it
- Health-promotion interventions targeting multiple behaviors: A meta-analytic review of general and behavior-specific processes of change.Psychological bulletin · 2024Pooled it
- Effect of vitamin BBMJ open · 2024Pooled it
- Pooled it
- Trial
- Trial
- Effect of core stabilization exercises on antioxidant/oxidant levels in hypertensives.Revista da Associacao Medica Brasileira (1992) · 2025Trial
- A comprehensive approach to lifestyle intervention based on a calorie-restricted diet ameliorates liver fat in overweight/obese patients with NAFLD: a multicenter randomized controlled trial in China.Nutrition journal · 2024Trial
- Trial
- Effects of Enhanced Nutritional Care in Heart Failure - A Systematic Review and Meta-Analysis.Circulation reports · 2026Review
- The impact of occupational hazards in coking plants on the incidence of hypertension-a longitudinal study.Frontiers in public health · 2026Article
- Contributions of Medications, Physical and Hydrotherapy Programs in Reducing Endothelial Dysfunction in Hypertensive Patients.Journal of functional morphology and kinesiology · 2025Article
- Exploration of pulse wave analysis under reactive hyperemia and close to an arteriovenous fistula: a comparative analysis.BMC cardiovascular disorders · 2025Article
- Markers of Vascular Dysfunction in Hypertension.Current medicinal chemistry · 2025Review
- Regulation of nitric oxide generation and consumption.International journal of biological sciences · 2025Review
- Review
- Reconstructive interpolation for pulse wave estimation to improve local PWV measurement of carotid artery.Medical & biological engineering & computing · 2024Article
- Sorting nexins: role in the regulation of blood pressure.The FEBS journal · 2023Review
- Longitudinal Associations between Alcohol Intake and Arterial Stiffness, Pressure Wave Reflection, and Inflammation.Journal of atherosclerosis and thrombosis · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Lifestyle modification is an important component of essential hypertension (EH) therapy. The aim of the Hypertension Intensive Nutrition Treatment (HINTreat) parallel, randomized controlled trial was to examine the effect of a 6-month intensive lifestyle treatment (ILT) (diet plus exercise with monthly visits) compared to the usual care. A total of 76 adults with stage 1 EH were randomized (38 in each group). Dietary analysis, anthropometry, physical activity, biochemical and urine profile, blood pressure (BP), asymmetric dimethylarginine (ADMA), central hemodynamics, β-stiffness index and carotid intima media-thickness were evaluated. The dietary inflammatory index (DII) was calculated for each participant from the intake of 29 nutrients/food components. At the end of the trial, participants in the ILT group reduced their 24h urinary Na excretion (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.