ReviewInternational journal of molecular sciences2020
Disruption of Placental Homeostasis Leads to Preeclampsia.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Review
- Shedding light on the function of autophagy in complicated pregnancies.Cell death & disease · 2026Review
- Predictive value of prenatal screening markers combined with serum placental growth factor in early pregnancy for preeclampsia.Pakistan journal of medical sciences · 2025Article
- Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta.Epigenetics · 2024Article
- Proteomic Profiles of Maternal Plasma Extracellular Vesicles for Prediction of Preeclampsia.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024Article
- Exploring the Importance of Differential Expression of Autophagy Markers in Term Placentas from Late-Onset Preeclamptic Pregnancies.International journal of molecular sciences · 2024Article
- Progress in Research on Biomarkers of Gestational Diabetes Mellitus and Preeclampsia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Review
- Molecular and immunological developments in placentas.Human immunology · 2021Review
- Aggrephagy Deficiency in the Placenta: A New Pathogenesis of Preeclampsia.International journal of molecular sciences · 2021Review
- Preeclampsia: From Cellular Wellness to Inappropriate Cell Death, and the Roles of Nutrition.Frontiers in cell and developmental biology · 2021Review
- Curcumin: Could This Compound Be Useful in Pregnancy and Pregnancy-Related Complications?Nutrients · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
Placental homeostasis is directly linked to fetal well-being and normal fetal growth. Placentas are sensitive to various environmental stressors, including hypoxia, endoplasmic reticulum stress, and oxidative stress. Once placental homeostasis is disrupted, the placenta may rebel against the mother and fetus. Autophagy is an evolutionally conservative mechanism for the maintenance of cellular and organic homeostasis. Evidence suggests that autophagy plays a crucial role throughout pregnancy, including fertilization, placentation, and delivery in human and mouse models. This study reviews the available literature discussing the role of autophagy in preeclampsia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.