Evidence map›Paper›PMID 32392575›Full record

ArticlePediatric research2020

Incidence rates and characteristics of pediatric onset psychogenic nonepileptic seizures.

Anne S Hansen, Charlotte U Rask, Maria Rodrigo-Domingo, Sofie G Pristed, Jakob Christensen, René E Nielsen

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Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Incidence and prevalence of functional neurological disorder: a systematic review.Journal of neurology, neurosurgery, and psychiatry · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
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  6. Article
  7. Article
  8. Article
  9. Stigma surrounding functional seizures.Pediatric research · 2020
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anne S HansenUnit for Psychiatric Research, Psychiatry, Aalborg University Hospital, Aalborg, Denmark. ansoha@rn.dk.
Charlotte U RaskDepartment of Child and Adolescent Psychiatry, Research Unit, Aarhus University Hospital, Aarhus, Denmark.
Maria Rodrigo-DomingoUnit for Psychiatric Research, Psychiatry, Aalborg University Hospital, Aalborg, Denmark.
Sofie G PristedUnit for Psychiatric Research, Psychiatry, Aalborg University Hospital, Aalborg, Denmark.
Jakob ChristensenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
René E NielsenUnit for Psychiatric Research, Psychiatry, Aalborg University Hospital, Aalborg, Denmark.
Aalborg University Hospital · DKAarhus University · DKAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric onset psychogenic nonepileptic seizures (PNES) is a highly disabling disorder and potentially misdiagnosed as epilepsy. Still, knowledge regarding PNES in children and adolescents is limited and data on both incidence and characteristics are scarce. This study investigated the incidence rate (IR) and clinical characteristics of pediatric onset PNES, including possible differences when having comorbid epilepsy.

methodsA population-based study of children and adolescents aged 5-17 years with an incident diagnosis of PNES in the Danish healthcare registries between 1996 and 2014. In total, 386 children and adolescents were included after assessment of diagnostic validity using medical record data.

resultsThe IR increased during the study period with the maximum IR observed in 2014 (7.4 per 100,000 person-years). A history of both neurologic and psychiatric problems as well as negative life events was identified. Comorbid epilepsy was confirmed for 55 cases (14.2%) and was associated with intellectual disabilities, school support and prolonged delay in PNES diagnosis.

conclusionsPNES are increasingly diagnosed in children and adolescents, and the clinical profile of both neurologic and psychiatric health problems underscores the need for collaborative pediatric and mental healthcare. These findings provide important information for future healthcare planning in this area. IMPACT: This nationwide study is the first to report population-based incidence rates of pediatric onset PNES documenting markedly increasing incidence rates between 1996 and 2014. A history of both neurologic and psychiatric problems as well as negative life events was identified for pediatric onset PNES. Comorbid epileptic seizures were associated with intellectual disabilities, school support and prolonged delay in PNES diagnosis. The clinical profile of both neurologic and psychiatric health problems underscores the need for collaborative pediatric and mental healthcare. The increasing number of children and adolescents diagnosed with PNES is important information for future healthcare planning in this area.

Indexed as

Mental HealthAdolescentAdolescent BehaviorAdolescent DevelopmentAge FactorsAge of OnsetChildChild BehaviorChild DevelopmentChild, PreschoolComorbidityDenmarkFemaleHumansIncidenceMale

Identifiers

PMID32392575
OpenAlexW3023271477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.