Evidence map›Paper›PMID 32392463›Full record

ArticleImmunity2020

Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.

Cedric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary J van Helden, Dorine Sichien, Nincy Debeuf, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens and 11 more

Open access · bronzeAbstract read
In one paragraph

Article in Immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 251 papers.

0numbers the graph read from it
0cells of the map it votes in
251citing papers in PubMed
19.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

251 citing papers in PubMed, 396 citations in OpenAlex.

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  20. Targeted lungScience advances · 2026
    Article

191 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 4 countries.

Cedric BosteelsLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Katrijn NeytLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Manon VanheerswynghelsLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Mary J van HeldenLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Dorine SichienLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Nincy DebeufLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Sofie De PrijckLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium.
Victor BosteelsDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium; Laboratory of ER Stress and Inflammation, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium.
Niels VandammeData Mining and Modeling for Biomedicine Group, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent 9000, Belgium.
Liesbet MartensData Mining and Modeling for Biomedicine Group, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent 9052, Belgium.
Yvan SaeysData Mining and Modeling for Biomedicine Group, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent 9000, Belgium.
Els LouagieArgenx BV, Ghent 9052, Belgium.
Manon LesageArgenx BV, Ghent 9052, Belgium.
David L WilliamsDepartment of Surgery and Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.
Shiau-Choot TangMalaghan Institute of Medical Research, Wellington 6012, New Zealand.
Johannes U MayerMalaghan Institute of Medical Research, Wellington 6012, New Zealand.
Franca RoncheseMalaghan Institute of Medical Research, Wellington 6012, New Zealand.
Charlotte L ScottLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent 9052, Belgium.
Hamida HammadLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium; Department of Pulmonary Medicine, Erasmus University Medical Center Rotterdam, Rotterdam 3015 GJ, the Netherlands.
Martin GuilliamsLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent 9052, Belgium. Electronic address: martin.guilliams@ugent.vib.be.
Bart N LambrechtLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent 9052, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent 9000, Belgium; Department of Pulmonary Medicine, Erasmus University Medical Center Rotterdam, Rotterdam 3015 GJ, the Netherlands. Electronic address: bart.lambrecht@ugent.be.
VIB-UGent Center for Inflammation Research · BEGhent University Hospital · BEMalaghan Institute of Medical Research · NZArgenx (Belgium) · BEGhent University · BEEast Tennessee State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenotypic and functional dichotomy between IRF8

Indexed as

ImmunityAntigen PresentationBiomarkersCell PlasticityDendritic CellsDisease SusceptibilityGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksImmunophenotypingInterferon Type IMacrophagesMonocytesOrgan SpecificityReceptors, FcRespirovirus InfectionsBiomarkersInterferon Type IReceptors, FcTranscription FactorsCD64convalescent serumdendritic cellFc receptorinf-cDC2inflammationIRF8monocytetranscription factortype 1 interferonvirus

Identifiers

PMID32392463
PMCPMC7207120
OpenAlexW3023852946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.