ArticleAge and ageing2020
The role of illness acuity on the association between frailty and mortality in emergency department patients referred to internal medicine.
Article in Age and ageing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 101 papers, 1 of them a synthesis that pooled it.
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Who cites it
101 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.
- Frailty and outcomes in adults undergoing systemic anticancer treatment: a systematic review and meta-analysis.Journal of the National Cancer Institute · 2025Pooled it
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- Frailty severity, survival and physician service costs among older adults: a linked cohort study from Nova Scotia, Canada.Age and ageing · 2026Article
- Emergency medicine physician-led care at the patient's residence: a cohort study of a mobile emergency unit.BMC emergency medicine · 2026Article
- Synthetic MRI Neuroimaging Correlates of Frailty: Correlations Between Frailty Scales and Brain Structural Integrity.Aging medicine (Milton (N.S.W)) · 2026Article
- The application value of frailty assessment tools in the perioperative period: A narrative review.Journal of anesthesia and translational medicine · 2026Review
- Advance care planning uptake in the severely frail.BMC palliative care · 2026Observational
- The role of clinical frailty in predicting mortality following surgery for infective endocarditis.Turk gogus kalp damar cerrahisi dergisi · 2026Article
- Exploring the Perception of Urinary Catheter Use in Older Surgical Patients: ADLs Matter.Nursing open · 2026Article
- Frailty scale with the best prediction of mortality in individuals diagnosed with acute coronary syndrome: systematic review and meta-analysis.Journal of geriatric cardiology : JGC · 2026Article
- Association Between Clinical Frailty and Antibiotic Resistance Among Older Patients with Fever in the Emergency Department.Antibiotics (Basel, Switzerland) · 2026Article
- Adverse Events in Older Adults at Risk for Dementia During Remote Physical Exercise and Cognitive Training.Canadian geriatrics journal : CGJ · 2026Article
- Electronic frailty index based on comprehensive geriatric assessment in primary care: feasibility, validity, and reliability.BMC geriatrics · 2026Article
- 30-day readmission risk after hip fracture: a qualitative study in the Midlands, United Kingdom.BMC geriatrics · 2026Observational
- Comparative prognostic performance of identification of seniors at risk tool and national early warning score for 30-day adverse outcomes in older emergency department patients.BMC emergency medicine · 2026Observational
- Protocol for a Pilot Two-Arm Crossover Randomized Controlled Trial of the ACTIVE Intervention for Older Adults with and Without Mild Dementia and Their Care Partners.Journal of clinical medicine · 2026Article
- Geriatric Syndromes and Mortality Among Hospitalized Older Adults.JAMA network open · 2026Observational
- Article
- The Role of the Clinical Frailty Scale in Stratifying Management of Older Adults with Acute Calculous Cholecystitis and Acute Gallstone Pancreatitis.International journal of general medicine · 2026Review
41 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundwe investigated whether two frailty tools predicted mortality among emergency department (ED) patients referred to internal medicine and how the level of illness acuity influenced any association between frailty and mortality.
methodstwo tools, embedded in a Comprehensive Geriatric Assessment (CGA), were the clinical frailty scale (CFS) and a 57-item deficit accumulation frailty index (FI-CGA). Illness acuity was assessed using the Canadian Triage and Acuity Scale (CTAS). We examined all-cause 30-day and 6-month mortality and time to death.
resultsin 808 ED patients (mean age ± SD 80.8 ± 8.8, 54.4% female), the mean FI-CGA score was 0.44 ± 0.14, and the CFS was 5.6 ± 1.6. A minority (307; 38%) were classified as having high acuity (CTAS: 1-2). The 30-day mortality rate was 17%; this increased to 34% at 6 months. Compared to well patients with low acuity, the risk of 30-day mortality was 22.5 times (95% CI: 9.35-62.12) higher for severely frail patients with high acuity; 53% of people with very severe frailty (CFS = 8) and high acuity died within 30 days. When acuity was low, the risk for 30-day mortality was significantly higher only among those with very high levels of frailty (CFS 7-9, FI-CGA > 0.5). When acuity was high, even lower levels of frailty (CFS 5-6, FI-CGA 0.4-0.5) were associated with higher 30-day mortality.
conclusionsacross levels of frailty, higher acuity increased mortality risk. When acuity was low, the risk was significant only when the degree of frailty was high, whereas when acuity was high, even lower levels of frailty were associated with greater mortality risk.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.