Evidence map›Paper›PMID 32392235›Full record

ArticlePloS one2020

Life expectancy and survival analysis of patients with diabetes compared to the non diabetic population in Bulgaria.

Konstantin Tachkov, Konstantin Mitov, Yordanka Koleva, Zornitsa Mitkova, Maria Kamusheva, Maria Dimitrova, Valentina Petkova, Alexandra Savova, Miglena Doneva, Dimitar Tcarukciev and 4 more

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Diabetes and restenosis.Cardiovascular diabetology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Konstantin TachkovFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Konstantin MitovFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Yordanka KolevaTulane University, New Orleans, Louisianna, United States of America.
Zornitsa MitkovaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Maria KamushevaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Maria DimitrovaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Valentina PetkovaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Alexandra SavovaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Miglena DonevaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Dimitar TcarukcievUniversity endocrinology hospital, Medical University of Sofia, "Ivan Penchev", Sofia, Bulgaria.
Vasil ValovNovoNordisk Pharma, Sofia, Bulgaria.
Galia AngelovaInstitute of informatics and informational technologies, Bulgarian academy of sciences, Sofia, Bulgaria.
Manoela ManovaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.
Guenka PetrovaFaculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria.ORCID 0000-0001-8116-5138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate the expected life expectancy in patients with diabetes in Bulgaria and to compare it to the expected life expectancy of the non-diabetic population in the country.

methodsIt is a retrospective observational population study on individuals diagnosed with diabetes, compared to the non-diabetic population in Bulgaria for the period 2012-2015. Data from the national diabetes register and national statistical institute were used to construct life-tables with probability of survival with t-test and Chi Square test. Confounder analysis was done by age, sex, and type of diabetes. All-cause mortality and deaths in diabetic patients were analyzed. Kaplan-Meier survival curves were constructed for each age group and a log-rank analysis was conducted.

resultsAverage life expectancy in the non-diabetic population, patients with Type 1 DM and with Type 2 DM is 74.8; 70.96 and 75.19 years, respectively. For 2012-2015 the mortality in the non-diabetic population remained constant and lower (average-1.48%) compared to type-1 DM (5.25%) and Type-2 (4.27%). Relative risk of death in diabetics was higher overall (12%), after the age of 70 before which the relative risk was higher for the non-diabetic population. This was observed as a trend in all analyzed years.

conclusionPatients with type 2 DM have a longer life-expectancy than patients with type-1 DM and overall Diabetics life expectancy equals that of the non-diabetic population, which could suggest improved disease control and its associated complications in Bulgaria. Male diabetics show slightly longer life expectancy than their counterparts in the non-diabetic population, by a marginal gain of 0.6 years for the entire observed period. Life expectancy in diabetic women increased by 1.3 years, which was not observed in the non-diabetic population. Prevalence of diabetes was higher for women. Improved diabetes control may explain this gain in life; however other studies are needed to confirm this.

Indexed as

Cause of DeathLife ExpectancyAdolescentAdultAgedAged, 80 and overBiometryBulgariaChildChild, PreschoolDiabetes MellitusFemaleHumansInfantKaplan-Meier EstimateLife Tables

Identifiers

PMID32392235
PMCPMC7213739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.