ArticlePLoS genetics2020
UVR8-mediated inhibition of shade avoidance involves HFR1 stabilization in Arabidopsis.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Plant Flavonoids: Biosynthesis, Regulation, and Roles in Biotic and Abiotic Stresses.Plant, cell & environment · 2026Review
- Conservation and divergence of UVR8 photoreceptor-mediated UV-B signaling in Marchantia polymorpha.Plant physiology · 2026Article
- Integration of light quality signals regulates ABA abundance and stomatal movements during seedling establishment.The New phytologist · 2026Article
- Sensory Perception of Fluctuating Light in Arabidopsis.Plant, cell & environment · 2025Article
- Lights, location, action: shade avoidance signalling over spatial scales.Journal of experimental botany · 2025Review
- Making the most of canopy light: shade avoidance under a fluctuating spectrum and irradiance.Journal of experimental botany · 2025Review
- Light regulates the synthesis and accumulation of plant secondary metabolites.Frontiers in plant science · 2025Review
- Photoreceptor-induced sinapate synthesis contributes to photoprotection in Arabidopsis.Plant physiology · 2024Article
- ELONGATED HYPOCOTYL5 (HY5) and HY5 HOMOLOGUE (HYH) maintain shade avoidance suppression in UV-B.The Plant journal : for cell and molecular biology · 2023Article
- Mechanisms of UV-B light-induced photoreceptor UVR8 nuclear localization dynamics.The New phytologist · 2022Article
- Article
- Pivotal roles of ELONGATED HYPOCOTYL5 in regulation of plant development and fruit metabolism in tomato.Plant physiology · 2022Article
- Transcriptome and metabolome analyses revealed that narrowband 280 and 310 nm UV-B induce distinctive responses in Arabidopsis.Scientific reports · 2022Article
- Layering contrasting photoselective filters improves the simulation of foliar shade.Plant methods · 2022Article
- Integration of light and hormone signaling pathways in the regulation of plant shade avoidance syndrome.aBIOTECH · 2021Review
- An autoregulatory negative feedback loop controls thermomorphogenesis in Arabidopsis.PLoS genetics · 2021Article
- A constitutively monomeric UVR8 photoreceptor confers enhanced UV-B photomorphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Regulation of Growth and Main Health-Promoting Compounds of Chinese Kale Baby-Leaf by UV-A and FR Light.Frontiers in plant science · 2021Article
- Photoreceptors Regulate Plant Developmental Plasticity through Auxin.Plants (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sun-loving plants perceive the proximity of potential light-competing neighboring plants as a reduction in the red:far-red ratio (R:FR), which elicits a suite of responses called the "shade avoidance syndrome" (SAS). Changes in R:FR are primarily perceived by phytochrome B (phyB), whereas UV-B perceived by UV RESISTANCE LOCUS 8 (UVR8) elicits opposing responses to provide a counterbalance to SAS, including reduced shade-induced hypocotyl and petiole elongation. Here we show at the genome-wide level that UVR8 broadly suppresses shade-induced gene expression. A subset of this gene regulation is dependent on the UVR8-stabilized atypical bHLH transcription regulator LONG HYPOCOTYL IN FAR-RED 1 (HFR1), which functions in part redundantly with PHYTOCHROME INTERACTING FACTOR 3-LIKE 1 (PIL1). In parallel, UVR8 signaling decreases protein levels of the key positive regulators of SAS, namely the bHLH transcription factors PHYTOCHROME INTERACTING FACTOR 4 (PIF4) and PIF5, in a COP1-dependent but HFR1-independent manner. We propose that UV-B antagonizes SAS via two mechanisms: degradation of PIF4 and PIF5, and HFR1- and PIL1-mediated inhibition of PIF4 and PIF5 function. This work highlights the importance of typical and atypical bHLH transcription regulators for the integration of light signals from different photoreceptors and provides further mechanistic insight into the crosstalk of UVR8 signaling and SAS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.