ArticlePLoS genetics2020
Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 61 citations in OpenAlex.
- Cytogenetic Analysis of Altitude-Associated Chromosome Variations inEcology and evolution · 2026Article
- Ecological opportunity and the onset of polyploid niche expansion waves.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- How environment and genetic architecture of unreduced gametes shape the establishment of autopolyploids.Heredity · 2026Article
- The two sub-genomes of the allotetraploid frog Xenopus laevis are evolving under similar selective pressure in extant populations.BMC genomics · 2025Article
- Polyploid Formation Through Disrupting Mitotic Sister Chromatid Separation of Spermatogonia based on espl1 Heterozygous Knockout in Fish.Molecular biology and evolution · 2025Article
- The Genetic Consequences of Range Expansion and Its Influence on Diploidization in Polyploids.The American naturalist · 2025Article
- Recent and Recurrent Autopolyploidization Fueled Diversification of Snow Carp on the Tibetan Plateau.Molecular biology and evolution · 2024Article
- Ploidy as a leaky reproductive barrier: mechanisms, rates and evolutionary significance of interploidy gene flow.Annals of botany · 2024Review
- Creating insect neopolyploid lines to study animal polyploid evolution.Evolutionary applications · 2024Article
- Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles.Systematic biology · 2024Article
- Interspecific transfer of genetic information through polyploid bridges.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The genetic consequences of range expansion and its influence on diploidization in polyploids.bioRxiv : the preprint server for biology · 2024Article
- Polyploidization of Indotyphlops braminus: evidence from isoform-sequencing.BMC genomic data · 2024Article
- Multi-omics resources for the Australian southern stuttering frog (Mixophyes australis) reveal assorted antimicrobial peptides.Scientific reports · 2024Article
- Polyploid Cancer Cell Models in Drosophila.Genes · 2024Review
- Recurrent allopolyploidizations diversify ecophysiological traits in marsh orchids (Dactylorhiza majalis s.l.).Molecular ecology · 2023Article
- Interploidy Introgression Shaped Adaptation during the Origin and Domestication History of Brassica napus.Molecular biology and evolution · 2023Article
- Global gradients in the distribution of animal polyploids.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Repeated colonization of alpine habitats by Arabidopsis arenosa viewed through freezing resistance and ice management strategies.Plant biology (Stuttgart, Germany) · 2022Article
- The Complex History of Genome Duplication and Hybridization in North American Gray Treefrogs.Molecular biology and evolution · 2022Article
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Authors and funding
12 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyploidy has played an important role in evolution across the tree of life but it is still unclear how polyploid lineages may persist after their initial formation. While both common and well-studied in plants, polyploidy is rare in animals and generally less understood. The Australian burrowing frog genus Neobatrachus is comprised of six diploid and three polyploid species and offers a powerful animal polyploid model system. We generated exome-capture sequence data from 87 individuals representing all nine species of Neobatrachus to investigate species-level relationships, the origin and inheritance mode of polyploid species, and the population genomic effects of polyploidy on genus-wide demography. We describe rapid speciation of diploid Neobatrachus species and show that the three independently originated polyploid species have tetrasomic or mixed inheritance. We document higher genetic diversity in tetraploids, resulting from widespread gene flow between the tetraploids, asymmetric inter-ploidy gene flow directed from sympatric diploids to tetraploids, and isolation of diploid species from each other. We also constructed models of ecologically suitable areas for each species to investigate the impact of climate on differing ploidy levels. These models suggest substantial change in suitable areas compared to past climate, which correspond to population genomic estimates of demographic histories. We propose that Neobatrachus diploids may be suffering the early genomic impacts of climate-induced habitat loss, while tetraploids appear to be avoiding this fate, possibly due to widespread gene flow. Finally, we demonstrate that Neobatrachus is an attractive model to study the effects of ploidy on the evolution of adaptation in animals.
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