Evidence map›Paper›PMID 32392097›Full record

ArticleJCO clinical cancer informatics2020

Quantitative Imaging Informatics for Cancer Research.

Andrey Fedorov, Reinhard Beichel, Jayashree Kalpathy-Cramer, David Clunie, Michael Onken, Jörg Riesmeier, Christian Herz, Christian Bauer, Andrew Beers, Jean-Christophe Fillion-Robin and 11 more

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Association ofBioMed research international · 2022
    Article
  5. Review
  6. Article
  7. Review
  8. NCI Imaging Data Commons.Cancer research · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Andrey FedorovDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Reinhard BeichelUniversity of Iowa, Iowa City, IA.
Jayashree Kalpathy-CramerMassachusetts General Hospital, Boston, MA.
David CluniePixelMed Publishing, Bangor, PA.
Michael OnkenOpenConnections, Oldenburg, Germany.
Jörg RiesmeierFreelancer, Oldenburg, Germany.
Christian HerzDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Christian BauerUniversity of Iowa, Iowa City, IA.
Andrew BeersMassachusetts General Hospital, Boston, MA.
Jean-Christophe Fillion-RobinKitware, Clifton Park, NY.
Andras LassoQueen's University, Kingston, ON, Canada.
Csaba PinterQueen's University, Kingston, ON, Canada.
Steve PieperIsomics, Cambridge, MA.
Marco NoldenGerman Cancer Research Center, Heidelberg, Germany.
Klaus Maier-HeinGerman Cancer Research Center, Heidelberg, Germany.
Markus D HerrmannDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Joel SaltzStony Brook University, Stony Brook, NY.
Fred PriorUniversity of Arkansas for Medical Sciences, Little Rock, AR.
Fiona FennessyDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
John BuattiUniversity of Iowa, Iowa City, IA.
Ron KikinisDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Funding

Quantitative Imaging to Assess Response in Cancer Therapy TrialsU01CA140206 · NCI · UNIVERSITY OF IOWA · PI BUATTI, JOHN M, CASAVANT, THOMAS L. · 2010 to 2019
$5.8M
Quantitative Image Informatics for Cancer Research (QIICR)U24CA180918 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FEDOROV, ANDRIY, KIKINIS, RON · 2013 to 2017
$4.0M
Tools to Analyze Morphology and Spatially Mapped Molecular DataU24CA180924 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI SALTZ, JOEL H. · 2014 to 2019
$3.6M
Quantitiative MRI of prostate cancer as a biomarker and guide for treatmentU01CA151261 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FENNESSY, FIONA · 2010 to 2014
$1.8M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENCI NIH HHS U01 CA140206NCI NIH HHS U01 CA151261NCI NIH HHS U24 CA180918NCI NIH HHS U24 CA180924
6 · The paper itself

Abstract

purposeWe summarize Quantitative Imaging Informatics for Cancer Research (QIICR; U24 CA180918), one of the first projects funded by the National Cancer Institute (NCI) Informatics Technology for Cancer Research program.

methodsQIICR was motivated by the 3 use cases from the NCI Quantitative Imaging Network. 3D Slicer was selected as the platform for implementation of open-source quantitative imaging (QI) tools. Digital Imaging and Communications in Medicine (DICOM) was chosen for standardization of QI analysis outputs. Support of improved integration with community repositories focused on The Cancer Imaging Archive (TCIA). Priorities included improved capabilities of the standard, toolkits and tools, reference datasets, collaborations, and training and outreach.

resultsFourteen new tools to support head and neck cancer, glioblastoma, and prostate cancer QI research were introduced and downloaded over 100,000 times. DICOM was amended, with over 40 correction proposals addressing QI needs. Reference implementations of the standard in a popular toolkit and standalone tools were introduced. Eight datasets exemplifying the application of the standard and tools were contributed. An open demonstration/connectathon was organized, attracting the participation of academic groups and commercial vendors. Integration of tools with TCIA was improved by implementing programmatic communication interface and by refining best practices for QI analysis results curation.

conclusionTools, capabilities of the DICOM standard, and datasets we introduced found adoption and utility within the cancer imaging community. A collaborative approach is critical to addressing challenges in imaging informatics at the national and international levels. Numerous challenges remain in establishing and maintaining the infrastructure of analysis tools and standardized datasets for the imaging community. Ideas and technology developed by the QIICR project are contributing to the NCI Imaging Data Commons currently being developed.

Indexed as

GlioblastomaMedical InformaticsProstatic NeoplasmsDiagnostic ImagingHumansMaleNational Cancer Institute (U.S.)United States

Identifiers

PMID32392097
PMCPMC7265794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.