Evidence map›Paper›PMID 32392078›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Lung Development Genes and Adult Lung Function.

Laura Portas, Miguel Pereira, Seif O Shaheen, Annah B Wyss, Stephanie J London, Peter G J Burney, Matthew Hind, Charlotte H Dean, Cosetta Minelli

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Genetic characterization of preschool wheeze phenotypes.The Journal of allergy and clinical immunology · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. The Developmental Origins of Asthma and COPD.Annual review of physiology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. The impact of child and adolescent health on adult respiratory health: the evidence, gaps and priorities.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  11. Article
  12. Towards early detection and disease interception of COPD across the lifespan.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  13. Article
  14. scFocus: Detecting branching probabilities in single-cell data with SAC.Computational and structural biotechnology journal · 2025
    Article
  15. Dysanapsis Genetic Risk Predicts Lung Function Across the Lifespan.American journal of respiratory and critical care medicine · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Laura PortasNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0003-1789-1893
Miguel PereiraNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0002-7830-2717
Seif O ShaheenInstitute of Population Health Sciences, Queen Mary University of London, London, United Kingdom.ORCID 0000-0002-7273-8691
Annah B WyssDepartment of Health and Human Services, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina.ORCID 0000-0002-9756-5205
Stephanie J LondonDepartment of Health and Human Services, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina.ORCID 0000-0003-4911-5290
Peter G J BurneyNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0001-8635-5678
Matthew HindNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0002-9966-9446
Charlotte H DeanNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0002-8846-5472
Cosetta MinelliNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0001-9166-3958
Imperial College London · GBNational Institute of Environmental Health Sciences · USMary Lyon Centre at MRC Harwell · GBQueen Mary University of London · GBRoyal Brompton & Harefield NHS Foundation Trust · GB

Funding

CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Genetic And Environmental Factors In Childhood Respiratory HealthZIAES049019 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.8M
Genetics and Environment in Adult Respiratory, Allergic and Cardiac diseaseZIAES043012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.4M
Genetic /Environment Factors In Nonmalignant Resp DisZ01ES043012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE JOAN · 1999 to 2008
$340k
Intramural NIH HHS Z01 ES043012Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NHLBI NIH HHS R01 HL105756
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Developmental BiologyGenetic Predisposition to DiseaseAdultAgedAged, 80 and overFemaleGenome-Wide Association StudyGrowth and DevelopmentHumansLungMaleMiddle AgedPolymorphism, Single NucleotideRespiratory Function TestsRespiratory Physiological PhenomenaRisk FactorsCOPDFEV1/FVCFVCgenetic association studyUK Biobank

Identifiers

PMID32392078
PMCPMC7491406
OpenAlexW3020905229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.