Evidence map›Paper›PMID 32391795›Full record

ArticleeLife2020

Temporal transcription factors determine circuit membership by permanently altering motor neuron-to-muscle synaptic partnerships.

Julia L Meng, Yupu Wang, Robert A Carrillo, Ellie S Heckscher

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Regulatory logic of neuronal differentiation in theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Regulatory logic of neuronal identity specification inbioRxiv : the preprint server for biology · 2025
    Article
  6. Article
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  10. Review
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  15. Review
  16. Structural and Functional Synaptic Plasticity Induced by Convergent Synapse Loss in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julia L MengDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0003-0364-4437
Yupu WangDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.
Robert A CarrilloDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-2067-9861
Ellie S HeckscherDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0001-7618-0616
University of Chicago · US

Funding

Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
IgSF protein interactions drive specificity in circuit wiring and synaptic elaborationR01NS123439 · NINDS · UNIVERSITY OF CHICAGO · PI CARRILLO, ROBERT ARNULFO · 2021 to 2025
$2.1M
Development of neuronal circuits for innate behaviorR01NS105748 · NINDS · UNIVERSITY OF CHICAGO · PI HECKSCHER, ELIZABETH (ELLIE) S · 2018 to 2022
$1.7M
Interactions Between IgSF Proteins in Neural Circuit FormationK01NS102342 · NINDS · UNIVERSITY OF CHICAGO · PI CARRILLO, ROBERT ARNULFO · 2017 to 2019
$684k
National Science Foundation DGE-1746045NIGMS NIH HHS T32 GM007183NINDS NIH HHS K01 NS102342NINDS NIH HHS R01 NS105748NINDS NIH HHS R01 NS123439
6 · The paper itself

Abstract

How circuit wiring is specified is a key question in developmental neurobiology. Previously, using the

Indexed as

AnimalsCell LineageDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalGenes, InsectHomeodomain ProteinsMotor NeuronsMusclesNeuromuscular JunctionPOU Domain FactorsStem CellsSynapsesTranscription Factorscas protein, DrosophilaDNA-Binding ProteinsDrosophila Proteinshb protein, DrosophilaHomeodomain Proteinspdm2 protein, DrosophilaPOU Domain FactorsTranscription Factorsdevelopmental biologyD. melanogastermotor neuronneuronal stem cellneurosciencetranscription factors

Identifiers

PMID32391795
PMCPMC7242025
OpenAlexW3021637797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.