Evidence map›Paper›PMID 32391627›Full record

Trial reportInternational wound journal2020

Cost-effectiveness of multi-layered silicone foam dressings for prevention of sacral and heel pressure ulcers in high-risk intensive care unit patients: An economic analysis of a randomised controlled trial.

Monira El Genedy, Elisabeth Hahnel, Tsenka Tomova-Simitchieva, William V Padula, Armin Hauß, Nils Löber, Ulrike Blume-Peytavi, Jan Kottner

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Dressings and topical agents for preventing pressure ulcers.The Cochrane database of systematic reviews · 2024
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Observational
  10. Review
  11. Prophylactic Sacral Dressing in Prevention of Pressure Injury among ICU Patients: A Systematic Review and Meta-analysis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Monira El GenedyClinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-5947-847X
Elisabeth HahnelClinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-1121-0540
Tsenka Tomova-SimitchievaClinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
William V PadulaDepartment of Pharmaceutical and Health Economics, School of Pharmacy, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-1161-6954
Armin HaußNursing Science, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-3666-4127
Nils LöberDepartment of Clinical Quality and Risk Management, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-1552-2114
Ulrike Blume-PeytaviClinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-3528-3752
Jan KottnerClinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-0750-3818
Clinical Research Center for Hair and Skin Science · DECharité - Universitätsmedizin Berlin · DEGhent University · BEUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pressure ulcer incidence is high in intensive care units. This causes a serious financial burden to healthcare systems. We evaluated the cost-effectiveness of multi-layered silicone foam dressings for prevention of sacral and heel pressure ulcers in addition to standard prevention in high-risk intensive care units patients. A randomised controlled trial to assess the efficacy of multi-layered silicone foam dressings to prevent the development of pressure ulcers on heels and sacrum among 422 intensive care unit patients was conducted. Direct costs for preventive dressings in the intervention group and costs for treatment of incident pressure ulcers in both groups were measured using a bottom-up approach. A cost-effectiveness analysis by calculating the incremental cost-effectiveness ratio using different assumptions was performed. Additional dressing and labour costs of €150.81 (€116.45 heels; €34.36 sacrum) per patient occurred in the intervention group. Treatment costs were €569.49 in the control group and €134.88 in the intervention group. The incremental cost-effectiveness ratio was €1945.30 per PU avoided (€8144.72 on heels; €701.54 sacrum) in the intervention group. We conclude that application of preventive dressings is cost-effective for the sacral area, but only marginal on heels for critically ill patients.

Indexed as

Pressure UlcerBandagesCost-Benefit AnalysisHeelHumansIntensive Care UnitsSacrumSiliconesSiliconescost-effectivenesscosts analysispressure ulcerpreventionpreventive dressings

Identifiers

PMID32391627
PMCPMC7948587
OpenAlexW3023952881

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.