COVID and the Renin-Angiotensin System: Are Hypertension or Its Treatments Deleterious?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

23 citing papers in PubMed.

1. Association of COVID-19 with Comorbidities: An Update.ACS pharmacology & translational science · 2023
   Review
2. Association of ACE2 Gene Variants with the Severity of COVID-19 Disease-A Prospective Observational Study.International journal of environmental research and public health · 2022
   Observational
3. Angiotensin-converting enzyme 2 and transmembrane protease serine 2 in female and male patients with end-stage kidney disease.European journal of clinical investigation · 2022
   Article
4. Association between COVID-19 Diagnosis and Coronary Artery Thrombosis: A Narrative Review.Biomedicines · 2022
   Review
5. Molecular Insights of SARS-CoV-2 Antivirals Administration: A Balance between Safety Profiles and Impact on Cardiovascular Phenotypes.Biomedicines · 2022
   Review
6. Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin-angiotensin-aldosterone system (RAAS) dysregulation.Chemico-biological interactions · 2022
   Review
7. Interactions of renin-angiotensin system and COVID-19: the importance of daily rhythms in ACE2, ADAM17 and TMPRSS2 expression.Physiological research · 2021
   Review
8. Venous thromboembolism in patients with COVID-19 infection: risk factors, prevention, and management.Seminars in vascular surgery · 2021
   Review
9. Potential detrimental role of soluble ACE2 in severe COVID-19 comorbid patients.Reviews in medical virology · 2021
   Review
10. COVID-19 in Chronic Kidney Disease: The Impact of Old and Novel Cardiovascular Risk Factors.Blood purification · 2021
    Review
11. The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline.Neuro-degenerative diseases · 2021
    Review
12. Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor.Nature genetics · 2020
    Article
13. Why Methodology Is Important: Coffee as a Candidate Treatment for COVID-19?Journal of clinical medicine · 2020
    Article
14. The hypercoagulable state in COVID-19: Incidence, pathophysiology, and management.Thrombosis research · 2020
    Review
15. Severe Acute Respiratory Distress Syndrome Secondary to Coronavirus 2 (SARS-CoV-2).The international journal of occupational and environmental medicine · 2020
    Review
16. Cardiovascular Complications Associated with COVID-19 and Potential Therapeutic~Strategies.International journal of molecular sciences · 2020
    Review
17. Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets.RSC advances · 2020
    Article
18. Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2.bioRxiv : the preprint server for biology · 2020
    Article
19. COVID-19: The Influence of ACE Genotype and ACE-I and ARBs on the Course of SARS-CoV-2 Infection in Elderly Patients.Clinical interventions in aging · 2020
    Review
20. ACE/ACE2 Ratio: A Key Also in 2019 Coronavirus Disease (Covid-19)?Frontiers in medicine · 2020
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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