Evidence map›Paper›PMID 32391062›Full record

ArticleFrontiers in genetics2020

Quantifying the Predictive Accuracy of a Polygenic Risk Score for Predicting Incident Cancer Cases : Application to the CARTaGENE Cohort.

Julianne Duhazé, Rodolphe Jantzen, Yves Payette, Thibault De Malliard, Catherine Labbé, Nolwenn Noisel, Philippe Broët

Abstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julianne DuhazéResearch Center, CHU Sainte-Justine, Montreal, QC, Canada.
Rodolphe JantzenResearch Center, CHU Sainte-Justine, Montreal, QC, Canada.
Yves PayetteCARTaGENE, CHU Sainte-Justine, Montreal, QC, Canada.
Thibault De MalliardCARTaGENE, CHU Sainte-Justine, Montreal, QC, Canada.
Catherine LabbéCARTaGENE, CHU Sainte-Justine, Montreal, QC, Canada.
Nolwenn NoiselCARTaGENE, CHU Sainte-Justine, Montreal, QC, Canada.
Philippe BroëtResearch Center, CHU Sainte-Justine, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing use of polygenic risk scores (PRS) there is a need for adapted methods to evaluate the predictivity of these tools. In this work, we propose a new pseudo-

Indexed as

breast cancerpolygenic risk scorepseudo-R2survival mixture modelsurvival models

Identifiers

PMID32391062
PMCPMC7193029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.