Evidence map›Paper›PMID 32391045›Full record

ArticleFrontiers in genetics2020

Association of PTEN Gene SNPs rs2299939 With PFS in Patients With Small Cell Lung Cancer Treated With Early Radiotherapy.

Chunbo Wang, Depeng Yang, Xiaoqing Zhang, Xiaohan Zhang, Lijun Yang, Pingping Wang, Wenyang Zhou, Huaxin Li, Yiqun Li, Huan Nie and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Chunbo WangDepartment of Radiotherapy, The Third Affiliated Hospital of Harbin Medical University, Harbin, China.
Depeng YangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Xiaoqing ZhangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Xiaohan ZhangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Lijun YangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Pingping WangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Wenyang ZhouSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Huaxin LiSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Yiqun LiSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Huan NieSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Yu LiSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Harbin Institute of Technology · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer has higher morbidity and mortality than most cancers. It is common that there are some phenomenons of secondary drug resistance, radiotherapy resistance and poor prognosis during the treatment of small cell lung cancer (SCLC). Recent studies revealed that the single-nucleotide polymorphisms (SNPs) are associated with the curative effect among patients with the same pathological type and stage. Our study analyzed the start time of radiotherapy and the relationship between PTEN gene rs2299939 polymorphisms and survival time among 116 SCLC patients. The results showed that early radiotherapy significantly improved the time of survival in patients compared with late radiotherapy (

Indexed as

PFSPTENradio-chemotherapyrs2299939SCLC

Identifiers

PMID32391045
PMCPMC7190978
OpenAlexW3018771626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.