ReviewFrontiers in plant science2020
Desensitization of ABA-Signaling: The Swing From Activation to Degradation.
Review in Frontiers in plant science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- Dry side of the core: a meta-analysis addressing the original nature of the ABA signalosome at the onset of seed imbibition.Frontiers in plant science · 2023Pooled it
- Article
- Abscisic acid interplay with phytohormones, plant growth regulators and signaling molecules in orchestrating an elaborate crosstalk for stress resilience in plants.Biologia futura · 2026Review
- Stratification overcomes ABA-mediated seed dormancy by uncoupling RGL2/ABI5 inhibition from α-amylase expression.Stress biology · 2026Article
- ABI5-binding proteins are substrates of key components in the ABA core signaling pathway affecting seeds.Plant physiology · 2026Article
- Genome-wide identification and functional characterization of PP2C genes in the wild relative of sweet potato Ipomoea trifida.BMC plant biology · 2025Article
- Pulled GA signal orchestration proteome reconfiguration and redundancy cycling via PtGA2ox10-mediated metabolic gatekeeping in Chinese pine seeds.Plant cell reports · 2025Article
- From Hormones to Harvests: A Pathway to Strengthening Plant Resilience for Achieving Sustainable Development Goals.Plants (Basel, Switzerland) · 2025Review
- Genome-wide association mapping for stay-green and stem reserve mobilization traits in wheat (Triticum aestivum L.) under combined heat and drought stress.Protoplasma · 2025Article
- Molecular profiling ofFrontiers in plant science · 2025Article
- The lowdown on breakdown: Open questions in plant proteolysis.The Plant cell · 2024Review
- Overexpression of PotatoInternational journal of molecular sciences · 2024Article
- bZIP Transcription Factors: Structure, Modification, Abiotic Stress Responses and Application in Plant Improvement.Plants (Basel, Switzerland) · 2024Review
- The F-box protein RhSAF destabilizes the gibberellic acid receptor RhGID1 to mediate ethylene-induced petal senescence in rose.The Plant cell · 2024Article
- Deciphering the regulatory networks involved in mild and severe salt stress responses in the roots of wild grapevine Vitis vinifera spp. sylvestris.Protoplasma · 2024Article
- Cellular forgetting, desensitisation, stress and ageing in signalling networks. When do cells refuse to learn more?Cellular and molecular life sciences : CMLS · 2024Review
- Exploring the allelopathic autotoxicity mechanism of ginsenosides accumulation under ginseng decomposition based on integrated analysis of transcriptomics and metabolomics.Frontiers in bioengineering and biotechnology · 2024Article
- Characterization ofPeerJ · 2024Article
- GIGANTEA-ENHANCED EM LEVEL complex initiates drought escape response via dual function of ABA synthesis and flowering promotion.Plant signaling & behavior · 2023Article
- CePP2C19 confers tolerance to drought by regulating the ABA sensitivity in Cyperus esculentus.BMC plant biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abscisic acid (ABA) is a key plant stress-signaling hormone that accumulates upon osmotic stresses such as drought and high salinity. Several proteins have been identified that constitute the ABA-signaling pathway. Among them ABA receptors (PYR/PYL/RCAR), co-receptor PP2Cs (protein phosphatases), SnRK2 kinases (SNF1-related protein kinases) and ABI5/ABFs (transcription factors) are the major components. Upon ABA signal, PYR/PYL receptors interact with and recruit PP2Cs, releasing SnRK2s kinases from sequestration with PP2Cs. This allows SnKR2s to promote the activation of downstream transcription factors of ABA pathway. However, apart from activation, ubiquitination and degradation of core proteins in the ABA pathway by the ubiquitin proteasome system is less explored. In this review we will focus on the recent findings about feedback regulation of ABA signaling core proteins through degradation, which is emerging as a critical step that modulates and eventually ceases the signal relay. Additionally, we also discuss the importance of the recently identified effector protein HOS15, which negatively regulate ABA-signaling through degradation of OST1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.