ReviewFrontiers in neuroanatomy2020
Anatomy and Connectivity of the Subthalamic Nucleus in Humans and Non-human Primates.
Review in Frontiers in neuroanatomy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Deep Brain Stimulation of the Subthalamic Nucleus Modulates Reward-Related Behavior: A Systematic Review.Frontiers in human neuroscience · 2020Pooled it
- Left Vagus Stimulation Modulates Contralateral Subthalamic β Power Improving the Gait in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2024Trial
- Mechanism and progress of deep brain stimulation in the treatment of neurological and psychiatric disorders.MedScience · 2026Review
- Neuroimaging evidence for a dopamine-independent association between motor cortex microstructure and Parkinson's disease severity.NPJ Parkinson's disease · 2026Article
- Clinical utility of evoked potentials for programming subthalamic deep brain stimulation in Parkinsons disease.NPJ Parkinson's disease · 2026Review
- Hyperdirect projections from the supplementary motor area mediate subthalamic stimulation effects on movement initiation and inhibition in Parkinson's disease.Brain communications · 2026Article
- BrainSTEM: A single-cell multiresolution fetal brain atlas reveals transcriptomic fidelity of human midbrain cultures.Science advances · 2025Article
- Preoperative network activity predicts the response to subthalamic DBS for Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Ventral STN stimulation is associated with improved axial motor outcomes in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Shared pathway-specific network mechanisms of dopamine and deep brain stimulation for the treatment of Parkinson's disease.Nature communications · 2025Article
- Subthalamic Deep Brain Stimulation: Mapping Non-Motor Outcomes to Structural Connections.Human brain mapping · 2025Article
- The expression of transcription factors in the human fetal subthalamic nucleus suggests its origin from the first hypothalamic prosomere.Brain structure & function · 2025Article
- Suicidal ideation after subthalamic stimulation in Parkinson's Disease: A critical concern.Brain & spine · 2025Article
- Structural Connectivity of the Basal Ganglia from Patient-Individual Tractography Is Key for Understanding the Effects of Deep Brain Stimulation in Parkinson's Disease.Stereotactic and functional neurosurgery · 2025Article
- Striking Efficacy of Pallidal Deep Brain Stimulation in a Patient with Predominant Abductor Laryngeal Dystonia: A Case Report.Movement disorders clinical practice · 2024Article
- Globus pallidus is not independent from striatal direct pathway neurons: an up-to-date review.Molecular brain · 2024Review
- Adolescents' pain-related ontogeny shares a neural basis with adults' chronic pain in basothalamo-cortical organization.iScience · 2024Article
- The anterior cingulate cortex controls the hyperactivity in subthalamic neurons in male mice with comorbid chronic pain and depression.PLoS biology · 2024Article
- Architecture of the subthalamic nucleus.Communications biology · 2024Review
- Contribution of the subthalamic nucleus to motor, cognitive and limbic processes: an electrophysiological and stimulation study in monkeys.Frontiers in neuroscience · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Subthalamic Nucleus (STh) is an oval-shaped diencephalic structure located ventrally to the thalamus, playing a fundamental role in the circuitry of the basal ganglia. In addition to being involved in the pathophysiology of several neurodegenerative disorders, such as Huntington's and Parkinson's disease, the STh is one of the target nuclei for deep brain stimulation. However, most of the anatomical evidence available derives from non-human primate studies. In this review, we will present the topographical and morphological organization of the nucleus and its connections to structurally and functionally related regions of the basal ganglia circuitry. We will also highlight the importance of additional research in humans focused on validating STh connectivity, cytoarchitectural organization, and its functional subdivision.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.