ReviewSeminars in plastic surgery2020
Osteoradionecrosis of the Maxilla: Conservative Management and Reconstructive Considerations.
Review in Seminars in plastic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Pentoxifylline and tocopherol for the treatment of osteoradionecrosis of the jaws. A systematic review.Medicina oral, patologia oral y cirugia bucal · 2023Pooled it
- Article
- Radiation-specific Automated Dosimetric dental, Mandible, and maxilla Annotation for Predicting Periodontal Problems (RADMAP): A semi-automated tool for dosimetric oral risk communication and osteoradionecrosis assessment.medRxiv : the preprint server for health sciences · 2025Article
- Risk factors associated with prognosis in patients with osteoradionecrosis of the jaws: A single institutional experience over 15 years.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Dose-finding and efficacy confirmation trial of the superselective intra-arterial infusion of cisplatin and concomitant radiation therapy for locally advanced maxillary sinus cancer (JCOG1212): final analysis.International journal of clinical oncology · 2025Article
- Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Article
- Oral health related-quality of life before and during the COVID-19 pandemic in patients with non-alcoholic fatty liver disease.Medicina oral, patologia oral y cirugia bucal · 2023Article
- Management of Palatal Defects after Free-Flap Reconstruction and Radiotherapy.Seminars in plastic surgery · 2023Review
- Osteoradionecrosis of the craniotomy flap: a rare complication of stereotactic radiosurgery.Oxford medical case reports · 2022Article
- Midface Degloving Approach for Total Maxillectomy Without Orbital Exenteration: A Case Series.OTO openArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The implementation of radiotherapy in the multimodal treatment of advanced head and neck cancer has greatly improved survival rates. In some patients, however, this benefit comes at the potential expense of the tissue surrounding the primary site of malignancy. Osteoradionecrosis (ORN) of the facial bones, in particular the maxilla, is a debilitating complication of radiation therapy. Exposure to ionizing radiation results in devitalization of underlying bone with necrosis of adjacent soft tissue. Controversy surrounding appropriate early intervention in ORN persists and no consensus for clinical treatment has been established. In the present article, we review the pathophysiology of maxillary ORN and discuss the role of both conservative medical therapy and reconstruction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.