Evidence map›Paper›PMID 32390707›Full record

ArticleWorld journal of gastroenterology2020

Severe steroid refractory gastritis induced by Nivolumab: A case report.

Helene Hjorth Vindum, Jørgen S Agnholt, Anders Winther Moelby Nielsen, Mette Bak Nielsen, Henrik Schmidt

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. A case series of immune checkpoint inhibitor-induced gastritis.Contemporary oncology (Poznan, Poland) · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Nivolumab-induced tumour-like gastritis: A case report.World journal of clinical cases · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Helene Hjorth VindumDepartment of Oncology, Aarhus University Hospital, Aarhus 8200, Denmark. helra9@rm.dk.
Jørgen S AgnholtDepartment of Gastroenterology, Aarhus University Hospital, Aarhus 8200, Denmark.
Anders Winther Moelby NielsenDepartment of Oncology, Aarhus University Hospital, Aarhus 8200, Denmark.
Mette Bak NielsenDepartment of Pathology, Aarhus University Hospital, Aarhus 8200, Denmark.
Henrik SchmidtDepartment of Oncology, Aarhus University Hospital, Aarhus 8200, Denmark.
Aarhus University Hospital · DKCreative Research Enterprises (United States) · USJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune checkpoint inhibitors are widely used for treatment of many advanced malignancies. Lower gastrointestinal (GI) side effects, such as diarrhea and colitis, are common, but upper GI side effects are rarely reported. Consequently, the correct treatment of upper GI adverse events has been less frequently described. CASE SUMMARY: We describe a case of a 16-year-old woman with stage IIIb malignant melanoma treated with adjuvant monotherapy using Nivolumab. The patient developed severe gastritis after six series of Nivolumab with weight loss, nausea, and vomiting. There was no effect of intravenous steroids, but the patient´s condition resolved after administration of Infliximab.

conclusionThis case report supports the same treatment for gastritis as for colitis, which is in line with current guidelines.

Indexed as

AdolescentChemotherapy, AdjuvantDrug ResistanceFemaleGastritisGlucocorticoidsHumansImmune Checkpoint InhibitorsInfliximabMelanomaNivolumabSeverity of Illness IndexSkin NeoplasmsTreatment OutcomeGlucocorticoidsImmune Checkpoint InhibitorsInfliximabNivolumabCase reportGastritisImmune checkpoint inhibitorsImmune-related adverse eventsInfliximabNivolumab

Identifiers

PMID32390707
PMCPMC7201147
OpenAlexW3022119467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.