ReviewWorld journal of gastroenterology2020
Malignant gastric outlet obstruction: Which is the best therapeutic option?
Review in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05561907 (Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction), which is not on this map. Cited by 65 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction: A Randomized Controlled Study Comparing Endoscopic Versus Surgical Gastrojejunostomy
Who cites it
65 citing papers in PubMed, 3 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Endoscopic ultrasonography-guided gastroenterostomy versus conventional approaches for cancer-related malignant gastrointestinal outlet obstruction: a meta-analysis with trial sequential analysis.Surgical endoscopy · 2026Pooled it
- Systematic review of long-term effectiveness of endoscopic gastrojejunostomy in patients presenting with gastric outlet obstruction from periampullary malignancies.Surgical endoscopy · 2024Pooled it
- A Meta-Analysis of Endoscopic Stenting Versus Surgical Treatment for Malignant Gastric Outlet Obstruction.World journal of surgery · 2023Pooled it
- Trial
- Latest advancements in endoscopic palliative care for patients with pancreatic cancer.Clinical endoscopy · 2026Review
- Therapeutic Endoscopic Ultrasound in Biliopancreatic Disease.Journal of clinical medicine · 2026Review
- Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report.Experimental and therapeutic medicine · 2026Article
- Palliative management of malignant gastric outlet obstruction: A practice review.Palliative medicine · 2026Review
- A Multi-State Cohort Study of Hospital Utilization and Treatment Modality for Malignant Gastrointestinal Obstructions.Journal of surgical oncology · 2026Article
- Endoscopic Ultrasound-Guided Lumen-Apposing Metal Stent Drainage in Benign Pancreatobiliary and Gastrointestinal Disease: Evolving Techniques and Clinical Outcomes.Diagnostics (Basel, Switzerland) · 2026Review
- Molecular Insights intoCancers · 2026Review
- Review
- The clinical effects of laparoscopic gastrojejunostomy versus nasointestinal tube insertion with subsequent chemotherapy for uncurable gastric cancer patients with outlet obstruction.Frontiers in oncology · 2026Article
- The Effect of Lumen-Apposing Metal Stent (LAMS) in Acute Cholecystitis Unfit for Surgery: Good Tidings.Diagnostics (Basel, Switzerland) · 2025Review
- Application of modified laparoscopic stomach-partitioning gastrojejunostomy for stage IV gastric cancer with gastric outlet obstruction.Journal of gastrointestinal oncology · 2025Article
- Review
- Surgical outcome of pediatric intestinal obstruction in Amhara comprehensive specialized hospitals, September 2024.BMC surgery · 2025Article
- Clinical utility of self-expandable metal stents in the treatment of anastomotic obstruction secondary to recurrent gastric cancer.Frontiers in oncology · 2025Article
- Treatment of choice for malignant gastric outlet obstruction: More than clearing the road.World journal of gastrointestinal endoscopy · 2024Article
- Palliation of Gastric Outlet Obstruction in Case of Biliary Obstruction-A Retrospective, Multicenter Study: The B-GOOD Study.Cancers · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant gastric outlet obstruction (MGOO) is a clinical condition characterized by the mechanical obstruction of the pylorus or the duodenum due to tumor compression/infiltration, with consequent reduction or impossibility of an adequate oral intake. MGOO is mainly secondary to advanced pancreatic or gastric cancers, and significantly impacts on patients' survival and quality of life. Patients suffering from this condition often present with intractable vomiting and severe malnutrition, which further compromise therapeutic chances. Currently, palliative strategies are based primarily on surgical gastrojejunostomy and endoscopic enteral stenting with self-expanding metal stents. Several studies have shown that surgical approach has the advantage of a more durable relief of symptoms and the need of fewer re-interventions, at the cost of higher procedure-related risks and longer hospital stay. On the other hand, enteral stenting provides rapid clinical improvement, but have the limit of higher stent dysfunction rate due to tumor ingrowth and a subsequent need of frequent re-interventions. Recently, a third way has come from interventional endoscopic ultrasound, through the development of endoscopic ultrasound-guided gastroenterostomy technique with lumen-apposing metal stent. This new technique may ideally encompass the minimal invasiveness of an endoscopic procedure and the long-lasting effect of the surgical gastrojejunostomy, and brought encouraging results so far, even if prospective comparative trial are still lacking. In this Review, we described technical aspects and clinical outcomes of the above-cited therapeutic approaches, and discussed the open questions about the current management of MGOO.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.