Evidence map›Paper›PMID 32390603›Full record

ArticleCancer biomarkers : section A of Disease markers2020

Prognostic value of miR-892a in gastric cancer and its regulatory effect on tumor progression.

Jingjing Lv, Haitao Zhang, Zhimei Gao, Xinyan Zhang, Xin Huang, Xiaojuan Jia

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PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer biomarkers : section A of Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jingjing LvDepartment of Pathology, Caoxian People's Hospital of Shandong, Heze, Shandong, China.
Haitao ZhangDepartment of Pathology, Chengwuxian People's Hospital of Shandong, Heze, Shandong, China.
Zhimei GaoDepartment of Pathology, Diseases in Caoxian Hospital of Traditional Chinese Medicine of Shandong, Heze, Shandong, China.
Xinyan ZhangDepartment of Clinical Laboratory, Caoxian Maternal and Child Health and Family Planning Service Center of Shandong, Heze, Shandong, China.
Xin HuangDepartment of Pathology, Caoxian People's Hospital of Shandong, Heze, Shandong, China.
Xiaojuan JiaDepartment of Pathology, Caoxian People's Hospital of Shandong, Heze, Shandong, China.
Cixian People's Hospital · CNShandong Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer is a prevalent malignant around the world. Aberrantly expression of microRNAs (miRNAs) contributes to the progression of tumors. The aim of this study was to investigate the expression and role of miR-892a in gastric cancer.

methodsA total of 119 gastric cancer patients were enrolled in this study. And the expression of miR-892a in gastric cancer tissues and cells was measured using RT-qPCR analysis. Kaplan-Meier plotter and multivariate Cox regression analysis were used to explore the prognostic value of miR-892a in gastric cancer. The biological function of miR-892a in gastric cancer cells was evaluated using CCK-8 assays and Transwell assays.

resultsThe expression of miR-892a was high-expressed in gastric cancer tissues and cells. The miR-892a expression was associated with tumor size, differentiation, lymph node metastasis, and TNM stages. Gastric cancer patients with high miR-892a expression showed a short overall survival rate. Overexpression of miR-892a promoted cell proliferation, migration, and invasion of gastric cancer cells.

conclusionmiR-892a was upregulated and predictor of poor prognosis in gastric cancer patients. The miR-892a in gastric cancer cells significantly promoted cell proliferative, migratory, and invasive properties. Furthermore, miR-892a may be served as a prognostic marker as well as a therapeutic target for gastric cancer.

Indexed as

Gene Expression Regulation, NeoplasticBiomarkers, TumorCell DifferentiationCell Line, TumorCell MovementCell ProliferationDisease ProgressionFemaleGastrectomyGastric MucosaGene Expression ProfilingHumansKaplan-Meier EstimateLymphatic MetastasisMaleMicroRNAsBiomarkers, TumorMicroRNAsMIRN892 microRNA, humanGastric cancerinvasionmigrationmiR-892aprognosisproliferation

Identifiers

PMID32390603
PMCPMC12662346
OpenAlexW3022831576

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.