Evidence map›Paper›PMID 32390527›Full record

ArticleJournal of the American Heart Association2020

Red Blood Cell Transfusion After Stage I Palliation Is Associated With Worse Clinical Outcomes.

Felina K Mille, Aditya Badheka, Priscilla Yu, Xuemei Zhang, David F Friedman, John Kheir, Sarah van den Bosch, Antonio G Cabrera, Javier J Lasa, Hannah Katcoff and 7 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  5. Article
  6. Variation in Neonatal Transfusion Practice.The Journal of pediatrics · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Felina K MilleThe Children's Hospital of Philadelphia Philadelphia PA.
Aditya BadhekaUniversity of Iowa Stead Family Children's Hospital Iowa City IA.
Priscilla YuUniversity of Texas Southwestern Medical Center Dallas TX.
Xuemei ZhangThe Children's Hospital of Philadelphia Philadelphia PA.
David F FriedmanThe Children's Hospital of Philadelphia Philadelphia PA.
John KheirBoston Children's Hospital Boston MA.
Sarah van den BoschBoston Children's Hospital Boston MA.
Antonio G CabreraTexas Children's Hospital Houston TX.
Javier J LasaTexas Children's Hospital Houston TX.
Hannah KatcoffThe Children's Hospital of Philadelphia Philadelphia PA.
Paula HuThe Children's Hospital of Philadelphia Philadelphia PA.
Santiago BorasinoUniversity of Alabama at Birmingham AL.
Krissie HockUniversity of Alabama at Birmingham AL.
Jordan HuskeyUniversity of Alabama at Birmingham AL.
Jamie WellerUniversity of Texas Southwestern Medical Center Dallas TX.
Harsh KothariUniversity of Iowa Stead Family Children's Hospital Iowa City IA.
Joshua BlinderThe Children's Hospital of Philadelphia Philadelphia PA.
Children's Hospital of Philadelphia · USUniversity of Alabama at Birmingham · USTexas Children's Hospital · USThe University of Texas Southwestern Medical Center · USBoston Children's Hospital · USBoston Children's Museum · USUniversity of Iowa · USUniversity of Iowa Stead Family Children’s Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Packed red blood cell transfusion may improve oxygen content in single-ventricle neonates, but its effect on clinical outcomes after Stage 1 palliation is unknown. Methods and Results Retrospective multicenter analysis of packed red blood cell transfusion exposures in neonates after Stage 1 palliation, excluding those with intraoperative mortality or need for extracorporeal membrane oxygenation. Transfusion practice variability was assessed, and multivariable regression used to identify transfusion risk factors. After propensity score adjustment for severity of illness, clinical outcomes were compared between transfused and nontransfused subjects. Of 396 subjects, 323 (82%) received 930 postoperative red blood cell transfusions. Packed red blood cell volume (median 9-42 mL/kg [

Indexed as

Palliative CareBlalock-Taussig ProcedureErythrocyte TransfusionHospital MortalityHumansInfant, NewbornIntensive Care UnitsLength of StayNorwood ProceduresRespiration, ArtificialRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited Statescongenital heart diseaseneonatesNorwood operationred blood cell transfusionsingle ventriclestage I palliation

Identifiers

PMID32390527
PMCPMC7660859
OpenAlexW3021634920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.