Evidence map›Paper›PMID 32390510›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Dietary fructose enhances angiotensin II-stimulated Na

Nianxin Yang, Nancy J Hong, Jeffrey L Garvin

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nianxin YangDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Nancy J HongDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Jeffrey L GarvinDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Case Western Reserve University · USUniversity of California, Davis · US

Funding

The Role of The Proximal Nephron In Salt-Sensitive HypertensionR01HL128053 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI GARVIN, JEFFREY L. · 2016 to 2024
$4.3M
HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) HL 128053NHLBI NIH HHS R01 HL128053
6 · The paper itself

Abstract

Angiotensin II (ANG II) stimulates proximal nephron transport via activation of classical protein kinase C (PKC) isoforms. Acute fructose treatment stimulates PKC and dietary fructose enhances ANG II's ability to stimulate Na

Indexed as

Angiotensin IIAnimalsCalciumDietary SugarsEnzyme ActivationFructoseKidney Tubules, ProximalMaleProtein Kinase C-alphaRats, Sprague-DawleyRenal ReabsorptionSodiumTime FactorsAngiotensin IICalciumDietary SugarsFructoseProtein Kinase C-alphaSodiumhypertensionintracellular calciumkidneysodium transporttranslocation

Identifiers

PMID32390510
PMCPMC7311708
OpenAlexW3022864642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.