Evidence map›Paper›PMID 32390111›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Test-retest repeatability and software reproducibility of myocardial flow measurements using rest/adenosine stress Rubidium-82 PET/CT with and without motion correction in healthy young volunteers.

Christina Byrne, Andreas Kjaer, Naja Enevold Olsen, Julie Lyng Forman, Philip Hasbak

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Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  4. Technical evaluation of immediate back-to-back rest-stress positron emission tomography scanning withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025
    Article
  5. Article
  6. Article
  7. Positron Range Correction Helps Enhance the Image Quality of CardiacJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Pulmonary blood volume assessment from a standard cardiac rubidium-82 imaging protocol: impact of adenosine-induced hyperemia.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  13. Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  14. Article
  15. Article
  16. Automated dynamic motion correction improves repeatability and reproducibility of myocardial blood flow quantification with rubidium-82 PET imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  17. Article
  18. Myocardial flow reserve estimation with contemporary CZT-SPECT andJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  19. Sex Differences and Caffeine Impact in Adenosine-Induced Hyperemia.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  20. More evidence for adequate test-retest repeatability of myocardial blood flow quantification withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christina ByrneDepartment of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, 9841, Blegdamsvej 9, 2100, Copenhagen, Denmark. hsz199@alumni.ku.dk.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Department of Biomedical Sciences, Copenhagen University Hospital Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Naja Enevold OlsenDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Department of Biomedical Sciences, Copenhagen University Hospital Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Julie Lyng FormanSection of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Philip HasbakDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Department of Biomedical Sciences, Copenhagen University Hospital Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyocardial flow reserve (MFR) assessment with cardiac positron emission computed tomography (PET/CT) is well established, and quantification relies on commercial software packages. However, for reliable use, repeatability and reproducibility are important. The aim of this study was therefore to investigate and compare between scans and software packages the repeatability and reproducibility of METHODS AND

resultsForty healthy volunteers completed two

conclusionsReproducibility of MFR varied for the different software. The highest concordance between MFRs was found between syngo.MBF and QGS.

Indexed as

Coronary CirculationExercise TestRubidium RadioisotopesSoftwareAdenosineAdultFemaleHumansMaleMovementMyocardial Perfusion ImagingPositron Emission Tomography Computed TomographyReference ValuesReproducibility of ResultsRestYoung AdultAdenosineRubidium-82Rubidium RadioisotopesMyocardial blood flowMyocardial flow reserveMyocardial perfusionPositron emission tomographyRepeatabilityReproducibility

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.