Evidence map›Paper›PMID 32389530›Full record

ArticleAmerican journal of preventive medicine2020

Mortality Following Nonfatal Opioid and Sedative/Hypnotic Drug Overdose.

Sidra Goldman-Mellor, Mark Olfson, Cristina Lidon-Moyano, Michael Schoenbaum

Open access · greenAbstract read
In one paragraph

Article in American journal of preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

  1. Nonfatal Drug Overdose in a National Sample of Adolescents by Intent and Substance, Medicaid 2016-2020.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Sidra Goldman-MellorDepartment of Public Health, School of Social Sciences, Humanities, and Arts, University of California, Merced, Merced, California. Electronic address: sgoldman-mellor@ucmerced.edu.
Mark OlfsonDepartment of Psychiatry, Columbia University, New York, New York.
Cristina Lidon-MoyanoUniversidad Internacional de Cataluña, Barcelona, Spain.
Michael SchoenbaumDivision of Services and Intervention Research, National Institute of Mental Health, Bethesda, Maryland.
Columbia University · USNational Institute of Mental Health · USUniversitat Internacional de Catalunya · ESUniversity of California, Merced · US

Funding

Long-term health of adolescent suicide attempters: Healthcare utilization morbidity and costs.R15MH113108 · NIMH · UNIVERSITY OF CALIFORNIA, MERCED · PI GOLDMAN-MELLOR, SIDRA · 2017 to 2017
$564k
NIMH NIH HHS R15 MH113108
6 · The paper itself

Abstract

introductionOpioid and sedative/hypnotic drug overdoses are major causes of morbidity in the U.S. This study compares 12-month incidence of fatal unintentional drug overdose, suicide, and other mortality among emergency department patients presenting with nonfatal opioid or sedative/hypnotic overdose.

methodsThis is a retrospective cohort study using statewide, longitudinally linked emergency department patient record and mortality data from California. Participants comprised all residents presenting to a licensed emergency department at least once in 2009-2011 with nonfatal unintentional opioid overdose, sedative/hypnotic overdose, or neither (a 5% random sample). Participants were followed for 1 year after index emergency department presentation to assess death from unintentional overdose, suicide, or other causes, ascertained using ICD-10 codes. Absolute death rates per 100,000 person years and standardized mortality ratios relative to the general population were calculated. Data were analyzed February-August 2019.

resultsFollowing the index emergency department visit, unintentional overdose death rates per 100,000 person years were 1,863 following opioid overdose, 342 following sedative/hypnotic overdose, and 31 for reference patients without an index overdose (respective standardized mortality ratios of 106.1, 95% CI=95.2, 116.9; 24.5, 95% CI=21.3, 27.6; and 2.6, 95% CI=2.2, 3.0). Suicide mortality rates per 100,000 were 319, 174, and 32 following opioid overdose, sedative/hypnotic overdose, and reference visits, respectively. Natural causes mortality rates per 100,000 were 8,058 (opioid overdose patients), 17,301 (sedative/hypnotic overdose patients), and 3,097 (reference patients).

conclusionsEmergency department patients with nonfatal opioid or sedative/hypnotic drug overdose have exceptionally high risks of death from unintentional overdose, suicide, and other causes. Emergency department-based interventions offer potential for reducing these patients' overdose and other mortality risks.

Indexed as

Analgesics, OpioidDrug OverdoseAdolescentAdultAgedChildFemaleHumansHypnotics and SedativesMaleMedicareMiddle AgedRetrospective StudiesUnited StatesYoung AdultAnalgesics, OpioidHypnotics and Sedatives

Identifiers

PMID32389530
PMCPMC7311279
OpenAlexW3021517011

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.