Evidence map›Paper›PMID 32388980›Full record

ArticleJournal of the American Chemical Society2020

Optical Manipulation of F-Actin with Photoswitchable Small Molecules.

Malgorzata Borowiak, Florian Küllmer, Florian Gegenfurtner, Sebastian Peil, Veselin Nasufovic, Stefan Zahler, Oliver Thorn-Seshold, Dirk Trauner, Hans-Dieter Arndt

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 89 citations in OpenAlex.

  1. Chemical reviews · 2026
    Review
  2. Crosstalk-Free Real-Time Precision Opto-Control of Biochemical Processes Through Intra-Pixel Optical Decoupling.Chemistry methods : new approaches to solving problems in chemistry · 2026
    Article
  3. SiR-XActin: A Fluorescent Probe for Imaging Actin Dynamics in Live Cells.Angewandte Chemie (International ed. in English) · 2025
    Article
  4. Recent advances in nuclear actin research.Nucleus (Austin, Tex.) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Deuteration as a General Strategy to Enhance Azobenzene-Based Photopharmacology.Angewandte Chemie (International ed. in English) · 2024
    Article
  11. Article
  12. Optical Control of G-Actin with a Photoswitchable Latrunculin.Journal of the American Chemical Society · 2024
    Article
  13. Spatiotemporally Precise Optical Manipulation of Intracellular Molecular Activities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  14. Article
  15. Review
  16. Turn-On Protein Switches for Controlling Actin Binding in Cells.bioRxiv : the preprint server for biology · 2023
    Article
  17. Review
  18. Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks.Angewandte Chemie (International ed. in English) · 2022
    Article
  19. Synthesis and Study of Dibenzo[Molecules (Basel, Switzerland) · 2022
    Article
  20. Journal of the American Chemical Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Malgorzata BorowiakDepartment of Pharmacy, Ludwig-Maximilians University, Butenandtstrasse 5-13, München D-81377, Germany.
Florian KüllmerInstitute for Organic Chemistry and Macromolecular Chemistry, Friedrich-Schiller-University, Humboldtstrasse 10, Jena D-07743, Germany.
Florian GegenfurtnerDepartment of Pharmacy, Ludwig-Maximilians University, Butenandtstrasse 5-13, München D-81377, Germany.
Sebastian PeilInstitute for Organic Chemistry and Macromolecular Chemistry, Friedrich-Schiller-University, Humboldtstrasse 10, Jena D-07743, Germany.
Veselin NasufovicInstitute for Organic Chemistry and Macromolecular Chemistry, Friedrich-Schiller-University, Humboldtstrasse 10, Jena D-07743, Germany.
Stefan ZahlerDepartment of Pharmacy, Ludwig-Maximilians University, Butenandtstrasse 5-13, München D-81377, Germany.ORCID 0000-0002-5140-7287
Oliver Thorn-SesholdDepartment of Pharmacy, Ludwig-Maximilians University, Butenandtstrasse 5-13, München D-81377, Germany.ORCID 0000-0003-3981-651X
Dirk TraunerDepartment of Chemistry, New York University, 100 Washington Square East, New York 10003, New York, United States.ORCID 0000-0002-6782-6056
Hans-Dieter ArndtInstitute for Organic Chemistry and Macromolecular Chemistry, Friedrich-Schiller-University, Humboldtstrasse 10, Jena D-07743, Germany.ORCID 0000-0002-0792-1422
Friedrich Schiller University Jena · DELudwig-Maximilians-Universität München · DENew York University · US

Funding

Optical Control of the Actin CytoskeletonR01GM126228 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DIRK HARTWIG TRAUNER · 2018 to 2026
$2.6M
NIGMS NIH HHS R01 GM126228
6 · The paper itself

Abstract

Cell-permeable photoswitchable small molecules, termed

Indexed as

ActinsAzo CompoundsDepsipeptidesMolecular ConformationPhotochemical ProcessesSmall Molecule LibrariesActinsazobenzeneAzo CompoundsDepsipeptidesjasplakinolideSmall Molecule Libraries

Identifiers

PMID32388980
PMCPMC8023282
OpenAlexW3023124296

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.