Evidence map›Paper›PMID 32388925›Full record

ArticleInternal medicine journal2021

Head-to-head comparison of cerebral blood flow single-photon emission computed tomography and

David P Nadebaum, Natasha Krishnadas, Aurora M T Poon, Victor Kalff, Meir Lichtenstein, Victor L Villemagne, Gareth Jones, Christopher C Rowe

Abstract read
In one paragraph

Article in Internal medicine journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Failed Performance on the Test of Memory Malingering and Misdiagnosis in Individuals with Early-Onset Dysexecutive Alzheimer's Disease.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2022
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

David P NadebaumDepartment of Molecular Imaging and Therapy, Austin Hospital, Melbourne, Victoria, Australia.
Natasha KrishnadasDepartment of Molecular Imaging and Therapy, Austin Hospital, Melbourne, Victoria, Australia.
Aurora M T PoonDepartment of Molecular Imaging and Therapy, Austin Hospital, Melbourne, Victoria, Australia.
Victor KalffDepartment of Nuclear Medicine, Austin Hospital, Melbourne, Victoria, Australia.
Meir LichtensteinDepartment of Nuclear Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Victor L VillemagneDepartment of Molecular Imaging and Therapy, Austin Hospital, Melbourne, Victoria, Australia.
Gareth JonesDepartment of Molecular Imaging and Therapy, Austin Hospital, Melbourne, Victoria, Australia.
Christopher C RoweDepartment of Molecular Imaging and Therapy, Austin Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0003-3910-2453

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical diagnosis of Alzheimer disease (AD) is only 70% accurate. Reduced cerebral blood flow (CBF) and metabolism in parieto-temporal and posterior cingulate cortex may assist diagnosis. While widely accepted that

aimsTo compare directly the accuracy of CBF-SPECT and

methodsA total of 126 patients, 56% with mild cognitive impairment and 44% with dementia, completed both CBF-SPECT and

resultsClinicians reported high diagnostic confidence in 83% of

conclusions

Indexed as

Alzheimer DiseaseCerebrovascular CirculationFluorodeoxyglucose F18HumansPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonFluorodeoxyglucose F1818F-fluoro-2-deoxyglucoseAlzheimer diseasepositron emission tomographysingle-photon emission computed tomography imaging

Identifiers

PMID32388925
PMCPMC8457212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.