Evidence map›Paper›PMID 32388740›Full record

ArticleAnnals of surgical oncology2020

Prognostic Impact of Preoperative Nutritional Risk in Patients Who Undergo Surgery for Pancreatic Adenocarcinoma.

Ilaria Trestini, Salvatore Paiella, Marta Sandini, Isabella Sperduti, Giovanni Elio, Tommaso Pollini, Davide Melisi, Alessandra Auriemma, Caterina Soldà, Clelia Bonaiuto and 12 more

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Article in Annals of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Preoperative Risk Factors in Patients With Pancreatic Cancer.Journal of clinical medicine research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Ilaria Trestini *Department of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Salvatore Paiella *General and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy. salvatore.paiella@univr.it.
Marta SandiniDepartment of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Isabella SperdutiBiostatistical Unit - Clinical Trials Center, Bio-Statistics Unit, Regina Elena National Cancer Institute, Rome, Italy.
Giovanni ElioGeneral and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Tommaso PolliniGeneral and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Davide MelisiDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Alessandra AuriemmaDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Caterina SoldàDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Clelia BonaiutoDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Daniela TregnagoDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Alice AvanciniBiomedical Sciences, Department of Medicine, University of Verona Hospital Trust, Verona, Italy.
Erica SecchettinGeneral and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Deborah BonaminiGeneral and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Massimo LanzaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Sara PilottoDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Giuseppe MalleoGeneral and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Roberto SalviaGeneral and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Chiara BovoHealthcare Department Administrator, Azienda Ospedaliera Universitaria Integrata (AOUI), Verona, Italy.
Luca GianottiDepartment of Surgery, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.
Claudio Bassi *General and Pancreatic Surgery Unit, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Michele Milella *Department of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNutritional derangements are common hallmarks of pancreatic cancer (PC). Their early detection and management are usually overlooked in routine practice. This study aimed to explore preoperative nutritional status and its prognostic value in patients undergoing surgery for PC.

methodsData from 73 patients who underwent surgery for PC from November 2015 to January 2018 at the General and Pancreatic Surgery Unit, The Pancreas Institute, University Hospital of Verona Hospital, Verona, Italy, were retrospectively evaluated. The Nutritional Risk Screening (NRS)-2002 was used to evaluate the preoperative nutritional risk. Body composition was assessed using bioimpedance vectorial analysis (BIVA) on the day prior to surgery. The effect of clinical, pathological, and nutritional characteristics on overall survival (OS) was investigated using a Cox and logistic regression model. Kaplan-Meier curves were compared using the log-rank test.

resultsMost patients (80.8%) were at preoperative risk of malnutrition (NRS-2002 ≥ 3) despite a mean BMI of 24.1 kg/m

conclusionsOur analysis confirms that preoperative malnutrition has a detrimental impact on OS in PC patients undergoing radical surgery for PC. Careful preoperative nutritional evaluation of PC patients should be mandatory, especially in those who are candidates for neoadjuvant therapy.

Indexed as

AdenocarcinomaPancreatic NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsHumansItalyNutritional StatusPrognosisRetrospective Studies

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.