Evidence map›Paper›PMID 32388672›Full record

ArticleInternational ophthalmology2020

Ciliary muscle dimensions measured by swept-source optical coherence tomography in eyes with primary open-angle glaucoma and healthy eyes.

Bachar Kudsieh, José Ignacio Fernández-Vigo, Hang Shi, Lucía De Pablo Gómez de Liaño, José María Ruiz-Moreno, Julián García-Feijóo, José Ángel Fernández-Vigo

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Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Bachar KudsiehDepartment of Ophthalmology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain. bacharkudsieh@gmail.com.ORCID http://orcid.org/0000-0002-2600-8233
José Ignacio Fernández-VigoCentro Internacional de Oftalmología Avanzada, Zurbano 71, 28010, Madrid, Spain.
Hang ShiCentro Internacional de Oftalmología Avanzada, Zurbano 71, 28010, Madrid, Spain.
Lucía De Pablo Gómez de LiañoDepartment of Ophthalmology, Hospital Universitario Doce De Octubre, Madrid, Spain.
José María Ruiz-MorenoDepartment of Ophthalmology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Julián García-FeijóoDepartment of Ophthalmology, San Carlos Clinical Hospital, Health Research Institute (IdISSC), Universidad Complutense, OFTARED, Madrid, Spain.
José Ángel Fernández-VigoCentro Internacional de Oftalmología Avanzada, Zurbano 71, 28010, Madrid, Spain.
Hospital Clínico San Carlos · ESHospital Universitario 12 De Octubre · ESHospital Universitario Puerta de Hierro Majadahonda · ESSpanish Agency for International Development Cooperation · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare in vivo swept-source optical coherence tomography (SS-OCT) measurements of the ciliary muscle (CM) in patients with primary open-angle glaucoma (POAG) and healthy subjects, and examine correlations between CM dimensions and several covariates.

methodsThis was a cross-sectional study of the right eyes of 181 subjects: 89 POAG patients and 92 healthy subjects. Using the Triton SS-OCT device (Topcon, Tokyo, Japan), CM length (CML), area (CMA) and thickness measured 1000 µm (CMT1), 2000 µm (CMT2) and 3000 µm (CMT3) from the scleral spur were determined in the temporal and nasal quadrants. POAG patients were subjected to visual field (VF) and peripapillary retinal nerve fiber layer (RNFL) assessment. CM dimensions were then assessed for correlation with VF mean defect (MD), mean RNFL thickness and intraocular pressure (IOP).

resultsMean CMLs were 4325 ± 340 µm and 4195 ± 843 µm for the healthy subjects and POAG patients, respectively (p = 0.17). Mean CM thicknesses were CMT1 = 546 ± 56 µm, CMT2 = 326 ± 44 µm and CMT3 = 174 ± 16 µm in the healthy eyes versus CMT1 = 534 ± 108, CMT2 = 332 ± 99 and CMT3 = 183 ± 74 in the POAG eyes, with no significant differences detected (all p ≥ 0.25). In the temporal quadrant, mean CMA was 1.12 ± 0.29 mm

conclusionsWhile SS-OCT proved useful to measure CM dimensions in vivo, these dimensions did not differ between healthy individuals and POAG subjects. In the patients with POAG, no correlations were detected between CM dimensions and VF, RNFL or IOP.

Indexed as

Glaucoma, Open-AngleOptic DiskCross-Sectional StudiesHumansIntraocular PressureJapanMusclesTomography, Optical CoherenceAnterior chamber angleCiliary bodyCiliary muscleGlaucomaOptical coherence tomography

Identifiers

PMID32388672
OpenAlexW3022395351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.