Evidence map›Paper›PMID 32388641›Full record

ArticleEuropean journal of clinical pharmacology2020

Pharmaceuticals and Environment: a web-based decision support for considering environmental aspects of medicines in use.

Helena Ramström, Siv Martini, Johanna Borgendahl, Marlene Ågerstrand, Gerd Lärfars, Marie-Louise Ovesjö

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in European journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05609864 (Drug Wastage), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05609864 completednot on this mapstarted 2023, after this paper: background citation

Drug Wastage : Observational Study in the Operating Rooms of France

TypeobservationalSponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2023 to 2023Enrolled3,763ConditionsDrug UseArmsQuantification of injectable drugs wastage
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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  6. Review
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  9. Developing an Ecotoxicological Classification for Frequently Used Drugs in Primary Care.International journal of environmental research and public health · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Helena RamströmHealth and Medical Care Administration, Region Stockholm, Box 6909, SE-102 39, Stockholm, Sweden. helena.ramstrom@sll.se.ORCID https://orcid.org/0000-0002-5093-6136
Siv MartiniFormerly at Health and Medical Care Administration, Region Stockholm, Stockholm, Sweden.
Johanna BorgendahlSustainability Department, Regional Executive Office, Region Stockholm, Stockholm, Sweden.
Marlene ÅgerstrandDepartment of Environmental Science, Stockholm University, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-2697-2310
Gerd LärfarsHealth and Medical Care Administration, Region Stockholm, Box 6909, SE-102 39, Stockholm, Sweden.
Marie-Louise OvesjöDivision of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0591-6208
Stockholm Health Care Services · SEKarolinska Institutet · SEStockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe database Pharmaceuticals and Environment is a non-commercial, freely available web-based decision support presenting compiled environmental information for pharmaceutical substances. It was developed by Region Stockholm and launched in 2016 at janusinfo.se. The purpose of this paper is to present the database, report on its current use, and reflect on lessons learned from developing and managing the database.

methodsA standard operating procedure describes the work and content of the database, e.g., how information is retrieved, processed, and presented. Google Analytics was used for metrics. Issues related to the database have been discussed and handled by a reference group. The experiences from this work are presented.

resultsThe database contains environmental hazard and risk information, primarily gathered from regulatory authorities and pharmaceutical companies. There are also assessments comparing substances within some groups of pharmaceuticals. The database is used by the Swedish Drug and Therapeutics Committees to include environmental aspects when recommending pharmaceuticals for health care providers. Page views show that users primarily look for information on commonly used substances, e.g., diclofenac and paracetamol/acetaminophen. Major problems for the development of the database are lack of data, lack of transparency, and discrepancies in the available environmental information.

conclusionIn the absence of an adequate decision support produced by the regulatory authorities, we find the database Pharmaceuticals and Environment to be useful for Swedish Drug and Therapeutics Committees and health care providers, and it is our belief that the information can be valuable also in other settings.

Indexed as

Databases, FactualDecision Support TechniquesEnvironmentPharmaceutical PreparationsInternetRisk AssessmentSwedenPharmaceutical PreparationsDecision supportEnvironmental classificationEnvironmental hazard assessmentsEnvironmental risk assessmentPharmaceuticals

Identifiers

PMID32388641
PMCPMC7351842
OpenAlexW3021549777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.