Evidence map›Paper›PMID 32388612›Full record

GuidelineEuropean journal of nuclear medicine and molecular imaging2020

EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0.

Silvia Morbelli, Giuseppe Esposito, Javier Arbizu, Henryk Barthel, Ronald Boellaard, Nico I Bohnen, David J Brooks, Jacques Darcourt, John C Dickson, David Douglas and 18 more

Open access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 4 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 4 syntheses or guidelines pooled it, 244 citations in OpenAlex.

  1. Pooled it
  2. IMovement disorders clinical practice · 2024
    Pooled it
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  7. Neuroimaging in Tremor.Seminars in neurology · 2026
    Review
  8. Characterization of open-source BSREM reconstruction forPhysical and engineering sciences in medicine · 2026
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  12. Visual and Semiquantitative Assessment ofJournal of clinical medicine · 2026
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 12 countries.

Silvia MorbelliIRCCS Ospedale Policlinico San Martino, Genoa, Italy. silvia.morbelli@unige.it.
Giuseppe EspositoNuclear Medicine, Department of Radiology, Medstar Georgetown University Hospital, 3800 Reservoir Road NW CCC Bldg, Washington, DC, 20007, USA.
Javier ArbizuDepartment of Nuclear Medicine, University of Navarra, Clinica Universidad de Navarra, IdiSNA, Pamplona, Spain.
Henryk BarthelDepartment of Nuclear Medicine, Leipzig University, Leipzig, Germany.
Ronald BoellaardDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, NeuroScience, De Boelelaan 1117, Amsterdam, The Netherlands.
Nico I BohnenDepartments Radiology & Neurology, University of Michigan & Ann Arbor Veterans Medical Center, Ann Arbor, MI, USA.
David J BrooksDepartment of Nuclear Medicine, Aarhus University, Aarhus, Denmark.
Jacques DarcourtNuclear Medicine, Department of imaging, Centre Antoine Lacassagne, Université Cote d'Azur, Nice, France.
John C DicksonInstitute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
David DouglasDepartment of Nuclear Medicine and Neuroradiology, Stanford University, Stanford, CA, USA.
Alexander DrzezgaDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Jacob DubroffDivision of Nuclear Medicine and Clinical Molecular Imaging in the Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Ozgul EkmekciogluDepartment of Nuclear Medicine, Sisli Etfal Education and Research Hospital, Istanbul, Turkey.
Valentina GaribottoNIMTLab, Faculty of Medicine, Geneva University, Geneva, Switzerland.
Peter HerscovitchPositron Emission Tomography Department, NIH/CC, Bethesda, MD, USA.
Phillip KuoDepartments of Medical Imaging, Medicine and Biomedical Engineering, University of Arizona, Tucson, AZ, USA.
Adriaan LammertsmaDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, NeuroScience, De Boelelaan 1117, Amsterdam, The Netherlands.
Sabina PappataNational Council of Research, Institute of Biostructure and Bioimaging, Naples, Italy.
Iván PeñuelasDepartment of Nuclear Medicine, University of Navarra, Clinica Universidad de Navarra, IdiSNA, Pamplona, Spain.
John SeibylInstitute for Neurodegenerative Disorders, New Haven, USA.
Franck SemahNuclear Medicine Department, University Hospital, Lille, France.
Livia Tossici-BoltMedical Physics, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Elsmarieke Van de GiessenRadiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Koen Van LaereNuclear Medicine and PET-MR Unit, Department of Imaging and Pathology, University Hospital and KU Leuven, Leuven, Belgium.
Andrea VarroneCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Michele WannerUniversity of Washington, Seattle, WA, USA.
George ZubalNuclear Medicine and CT, NIH/NIBIB, Bethesda, USA.
Ian LawDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Clinica Universidad de Navarra · ESAmsterdam University Medical Centers · NLBanner - University Medical Center Tucson · USCentre Antoine Lacassagne · FRGeorgetown University · USInstitute for Neurodegenerative Disorders · USInstitute of Biostructure and Bioimaging · ITJülich Aachen Research Alliance · DEKU Leuven · BELeipzig University · DENational Institute of Biomedical Imaging and Bioengineering · USNewcastle University · GBOspedale Policlinico San Martino · ITPositron (United States) · USŞişli Etfal Eğitim ve Araştırma Hastanesi · TRStanford University · USStockholm Health Care Services · SEUniversity College London · GBUniversity Hospital of Geneva · CHUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addictionK23DA038726 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI DUBROFF, JACOB · 2016 to 2020
$964k
NIDA NIH HHS K23 DA038726
6 · The paper itself

Abstract

purposeThis joint practice guideline or procedure standard was developed collaboratively by the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI). The goal of this guideline is to assist nuclear medicine practitioners in recommending, performing, interpreting, and reporting the results of dopaminergic imaging in parkinsonian syndromes.

methodsCurrently nuclear medicine investigations can assess both presynaptic and postsynaptic function of dopaminergic synapses. To date both EANM and SNMMI have published procedural guidelines for dopamine transporter imaging with single photon emission computed tomography (SPECT) (in 2009 and 2011, respectively). An EANM guideline for D2 SPECT imaging is also available (2009). Since the publication of these previous guidelines, new lines of evidence have been made available on semiquantification, harmonization, comparison with normal datasets, and longitudinal analyses of dopamine transporter imaging with SPECT. Similarly, details on acquisition protocols and simplified quantification methods are now available for dopamine transporter imaging with PET, including recently developed fluorinated tracers. Finally, [

conclusionAll these emerging issues are addressed in the present procedural guidelines for dopaminergic imaging in parkinsonian syndromes.

Indexed as

Nuclear MedicineParkinsonian DisordersHumansMolecular ImagingRadionuclide ImagingTomography, Emission-Computed, Single-PhotonBrainDATDOPAParkinsonParkinsonian syndromesPETSPECT

Identifiers

PMID32388612
PMCPMC7300075
OpenAlexW2954129211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.