Evidence map›Paper›PMID 32388270›Full record

ArticleRedox biology2020

Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension.

Mi Ra Noh, Min Jung Kong, Sang Jun Han, Jee In Kim, Kwon Moo Park

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  7. Fine-mapping causal tissues and genes at disease-associated loci.medRxiv : the preprint server for health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mi Ra NohDepartment of Anatomy, Cardiovascular Research Center and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu, 41944, Republic of Korea.
Min Jung KongDepartment of Anatomy, Cardiovascular Research Center and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu, 41944, Republic of Korea.
Sang Jun HanDepartment of Anatomy, Cardiovascular Research Center and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu, 41944, Republic of Korea.
Jee In KimDepartment of Molecular Medicine, Keimyung University School of Medicine, 1095 Dalgubeol-daero, Dalseogu, Daegu, 42601, Republic of Korea.
Kwon Moo ParkDepartment of Anatomy, Cardiovascular Research Center and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu, 41944, Republic of Korea. Electronic address: kmpark@knu.ac.kr.
Kyungpook National University · KRKeimyung University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of hypertension is associated with mitochondrial redox balance disruptions. NADP

Indexed as

HypertensionIsocitrate DehydrogenaseAnimalsApoptosisDiet, High-FatMaleMiceMice, Inbred C57BLMice, KnockoutOxidative StressIsocitrate DehydrogenaseHypertensionIsocitrate dehydrogenase 2MitochondriaReactive oxygen speciesRenin-angiotensin system

Identifiers

PMID32388270
PMCPMC7210593
OpenAlexW3019765857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.