ReviewWorld neurosurgery2020
Neurological Impact of Coronavirus Disease of 2019: Practical Considerations for the Neuroscience Community.
Review in World neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings.BMC infectious diseases · 2021Pooled it
- Status epilepticus and COVID-19: A systematic review.Epilepsy & behavior : E&B · 2021Pooled it
- COVID-19 Postacute Sequela Rehabilitation: A Look to the Future Through the Lens of Chronic Obstructive Pulmonary Disease and Pulmonary Rehabilitation.Archives of rehabilitation research and clinical translation · 2022Article
- Potential neurological manifestations of COVID-19: a narrative review.Postgraduate medicine · 2022Review
- Neurological involvement associated with COVID-19 disease: a study on psychosocial factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Global survey on disruption and mitigation of neurological services during COVID-19: the perspective of global international neurological patients and scientific associations.Journal of neurology · 2022Article
- Suicide attempts among college students hospitalized for COVID-19.Journal of affective disorders · 2021Article
- Neuropsychiatric Disorders and COVID-19: What We Know So Far.Pharmaceuticals (Basel, Switzerland) · 2021Review
- The role of 5-lipoxygenase in the pathophysiology of COVID-19 and its therapeutic implications.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021Review
- Analysis of Neurosurgical Cases Before and During the Coronavirus Disease 2019 Pandemic from a Tertiary-Care Centre in India.World neurosurgery · 2021Article
- Incidence, clinical characteristics, risk factors and outcomes of meningoencephalitis in patients with COVID-19.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- A rapid review of the pathoetiology, presentation, and management of delirium in adults with COVID-19.Journal of psychosomatic research · 2021Review
- Emergent Carotid Artery Stenting Following Intravenous Alteplase Infusion After Rapid Negative Diagnosis for COVID-19 by Loop-Mediated Isothermal Amplification Assay.World neurosurgery · 2021Article
- The neurological symptoms of COVID-19: a systematic overview of systematic reviews, comparison with other neurological conditions and implications for healthcare services.Therapeutic advances in chronic disease · 2021Review
- Observational cohort study of neurological involvement among patients with SARS-CoV-2 infection.Therapeutic advances in neurological disorders · 2021Article
- Neurological manifestations of COVID-19 infection: an umbrella review.The Egyptian journal of neurology, psychiatry and neurosurgery · 2021Review
- Neuroethical and Societal Challenges of 21st Century Epidemics.Trends in neurosciences · 2020Review
- Letter to the Editor Regarding "Neurological Impact of Coronavirus Disease (COVID-19): Practical Considerations for the Neuroscience Community".World neurosurgery · 2020Article
- The COVID-19 rehabilitation pandemic.Age and ageing · 2020Article
- Electroencephalogram (EEG) in COVID-19: A systematic retrospective study.Neurophysiologie clinique = Clinical neurophysiology · 2020Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe coronavirus disease of 2019 (COVID-19), which is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently been designated a pandemic by the World Health Organization, affecting 2.7 million individuals globally as of April 25, 2020, with more than 187,000 deaths. An increasing body of evidence has supported central nervous system involvement.
methodsWe conducted a review of the reported data for studies concerning COVID-19 pathophysiology, neurological manifestations, and neuroscience provider recommendations and guidelines.
resultsCentral nervous system manifestations range from vague nonfocal complaints to severe neurological impairment associated with encephalitis. It is unclear whether the neurological dysfunction results from direct viral injury or systemic disease. The virus could affect brainstem pathways that lead to indirect respiratory dysfunction, in addition to direct pulmonary injury. Necessary adaptations in patient management, triage, and diagnosis are evolving in light of the ongoing scientific and clinical findings.
conclusionsThe present review has consolidated the current body of data regarding the neurological impact of coronaviruses, discussed the reported neurological manifestations of COVID-19, and highlighted the recommendations for patient management. Specific recommendations pertaining to clinical practice for neurologists and neurosurgeons have also been provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.