ArticleJournal of biomechanics2020
On the in vivo systolic compressibility of left ventricular free wall myocardium in the normal and infarcted heart.
Article in Journal of biomechanics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Physics-Informed Reconstruction of Transmural Myocardial Deformation from 3D Echocardiography: Validation Against Cardiac MRI.Annals of biomedical engineering · 2026Article
- A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves.Advanced healthcare materials · 2026Article
- Discovering dispersion: How robust is automated model discovery for human myocardial tissue?Biomechanics and modeling in mechanobiology · 2025Article
- Article
- The role of transient receptor potential melastatin channels in compressive force-induced contraction of primary cardiac pericytes.Physiological reports · 2025Article
- In-silico heart model phantom to validate cardiac strain imaging.Computers in biology and medicine · 2024Article
- In-silico heart model phantom to validate cardiac strain imaging.bioRxiv : the preprint server for biology · 2024Article
- A multi-scale computational model for the passive mechanical behavior of right ventricular myocardium.Journal of the mechanical behavior of biomedical materials · 2023Article
- Backscatter tensor imaging and 3D speckle tracking for simultaneous ex vivo structure and deformation measurement of myocardium.Ultrasound in medicine & biology · 2023Article
- Contractile Adaptation of the Left Ventricle Post-myocardial Infarction: Predictions by Rodent-Specific Computational Modeling.Annals of biomedical engineering · 2023Article
- Patient-Specific Inverse Modeling of In Vivo Cardiovascular Mechanics with Medical Image-Derived Kinematics as Input Data: Concepts, Methods, and Applications.Applied sciences (Basel, Switzerland) · 2022Article
- The impact of myocardial compressibility on organ-level simulations of the normal and infarcted heart.Scientific reports · 2021Article
- DeepStrain: A Deep Learning Workflow for the Automated Characterization of Cardiac Mechanics.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Although studied for many years, there remain continued gaps in our fundamental understanding of cardiac kinematics, such as the nature and extent of heart wall volumetric changes that occur over the cardiac cycle. Such knowledge is especially important for accurate in silico simulations of cardiac pathologies and in the development of novel therapies for their treatment. A prime example is myocardial infarction (MI), which induces profound, regionally variant maladaptive remodeling of the left ventricle (LV) wall. To address this problem, we conducted an in vivo fiduciary marker-based study in an established ovine model of MI to generate detailed, time-evolving transmural in vivo volumetric measurements of LV free wall deformations in the normal state, as well as up to 12 h post-MI. This was accomplished using a transmural array of sonomicrometry crystals that acquired fiducial positions at ∼250 Hz with a positional accuracy of ∼0.1 mm, covering the entire infarct, border, and remote zones. A convex-hull method was used to directly calculate the Jacobian J(t)=Δv(t)/ΔV
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