Evidence map›Paper›PMID 32385891›Full record

ReviewDermatologic therapy2020

Systemic immunobiological, immunosuppressant, and oncologic agents for the treatment of dermatologic diseases during the SARS-CoV-2 (COVID-19) pandemic emergency: A quick review for a quick consultation.

Giovanni Paolino, Santo Raffaele Mercuri, Pietro Bearzi, Carlo Mattozzi

Open access · bronzeAbstract readReview
In one paragraph

Review in Dermatologic therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Giovanni PaolinoDermatology Clinic, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-3032-2217
Santo Raffaele MercuriUnit of Dermatology, IRCCS San Raffaele Hospital, Milan, Italy.ORCID 0000-0002-9175-4574
Pietro BearziUnit of Dermatology, IRCCS San Raffaele Hospital, Milan, Italy.ORCID 0000-0002-7621-1192
Carlo MattozziDermatology Clinic, Sapienza University of Rome, Rome, Italy.
Vita-Salute San Raffaele University · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precision medicine era has helped to better manage patients with immunological and oncological diseases, improving the quality of life of this class of patients. Regarding the management of these patients and positivity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), currently, limited data are available and information is evolving. In this quick review, we have analyzed the mechanisms of action and related infective risk of drugs used for the treatment of immune-mediated and oncologic skin conditions during the daily clinical practice. In general, immunosuppressant and antineoplastic agents for dermatologic treatments do not require suspension and do not require special measures, if not those commonly observed. In the case of a coronavirus disease (COVID-19) patient with complications (such as pneumonia, respiratory failure), treatment suspension should always be considered after taking into account the general condition of the patient, the risk-benefit ratio, and the pathophysiology of COVID-19 infection. The COVID-19 emergency pandemic does not imply undertreatment of existing skin conditions, which together with the SARS-CoV-2 infection may jeopardize the patient's life.

Indexed as

Referral and ConsultationSARS-CoV-2Antineoplastic AgentsCOVID-19Emergency TreatmentHumansImmune Checkpoint InhibitorsImmunosuppressive AgentsSkin DiseasesSkin NeoplasmsAntineoplastic AgentsImmune Checkpoint InhibitorsImmunosuppressive AgentsbiologicsCOVID-19dermatologic treatmentsimmunosuppressantsSARS-CoV-2skin diseasetherapy systemic

Identifiers

PMID32385891
PMCPMC7261970
OpenAlexW3023439362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.