ArticleNeurocritical care2021
Respiratory and Blood Stream Infections are Associated with Subsequent Venous Thromboembolism After Primary Intracerebral Hemorrhage.
Article in Neurocritical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- A systematic review and meta-analysis show a decreasing prevalence of post-stroke infections.BMC neurology · 2024Pooled it
- Anemia From Inflammation After Intracerebral Hemorrhage and Relationships With Outcome.Journal of the American Heart Association · 2024Trial
- Risk Factors and Outcomes Associated with Atrial Fibrillation Detected after Intracerebral Hemorrhage.Neurocritical care · 2026Article
- Venous Thromboembolism in Severe Community-Acquired Pneumonia at High-Altitude Areas: Prevalence, Risk and Outcome.The clinical respiratory journal · 2026Article
- Risk factors for deep venous thrombosis in spontaneous intracerebral hemorrhage and their long-term prognostic implications.Open medicine (Warsaw, Poland) · 2026Article
- Deep vein thrombosis in severe community-acquired pneumonia patients undergoing thromboprophylaxis: Prevalence, risk factors, and outcome.Thrombosis journal · 2025Article
- Admission Viscoelastic Hemostatic Assay Parameters Predict Poor Long-Term Intracerebral Hemorrhage Outcomes.Neurocritical care · 2025Article
- Predictive Value of Cardiac Biomarkers Combined with Clinical, Radiological Factors for Venous Thromboembolism in Patients with Spontaneous Intracerebral Hemorrhage.Cerebrovascular diseases extra · 2025Article
- Development of an interpretable machine learning model for predicting venous thromboembolism in intensive care unit patients with intracerebral hemorrhage.Frontiers in neurology · 2025Article
- To develop a machine learning-based model for predicting the risk of gastrointestinal bleeding in patients with spontaneous intracerebral hemorrhage.Frontiers in neurology · 2025Article
- Admission viscoelastic hemostatic assay parameters predict poor long-term intracerebral hemorrhage outcomes.Research square · 2024Article
- Neutrophil-to-Lymphocyte ratio on admission predicts gastrointestinal bleeding in acute basal ganglia hemorrhage.Journal of clinical laboratory analysis · 2022Article
- Review
- A novel risk score to predict deep vein thrombosis after spontaneous intracerebral hemorrhage.Frontiers in neurology · 2022Article
- Patients with venous thromboembolism after spontaneous intracerebral hemorrhage: a review.Thrombosis journal · 2021Review
- Vascular Manifestations of COVID-19 - Thromboembolism and Microvascular Dysfunction.Frontiers in cardiovascular medicine · 2020Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfection and venous thromboembolism (VTE) are associated with worse outcomes after intracerebral hemorrhage (ICH). The relationship between infection and VTE in ICH patients is unclear. We hypothesized that infection would be associated with subsequent VTE after ICH.
methodsWe retrospectively studied consecutively admitted spontaneous primary ICH patients from 2009 to 2018 surviving beyond 24 h. The primary predictor variable was infection, diagnosed prior to VTE. The primary outcome was VTE. We used multivariable logistic regression models to estimate the odds ratios and 95% confidence intervals (OR, 95% CI) for VTE risk after infection of any type, after adjusting for ICH score, length of stay and days to deep venous thrombosis (DVT) prophylaxis. Similar analysis was done to estimate the association of infection subtypes, including respiratory and urinary and blood stream infections (BSI) with VTE.
resultsThere were 414 patients (mean age 65 years, 47% female) that met were analyzed. Infection was diagnosed in 181 (44%) patients. Incident VTE was diagnosed in 36 (9%) patients, largely comprised of DVT (n = 32; 89%). Infection overall was associated with increased risk of subsequent VTE (adjusted OR 4.5, 95% CI 1.6-12.6). Respiratory (adjusted OR 5.7, 95% CI 2.8-11.7) and BSI (adjusted OR 4.0, 95% CI 1.3-11.0) were associated with future VTE. Urinary and other infections were not associated with subsequent VTE.
conclusionsInfections are associated with subsequent risk of VTE among patients with ICH. Further investigation is required to elucidate mechanisms behind this association and to improve VTE prevention after ICH.
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