Evidence map›Paper›PMID 32385745›Full record

ReviewAdvances in therapy2020

Malignant Transformation and Associated Biomarkers of Ovarian Endometriosis: A Narrative Review.

Liudmila M Mikhaleva, Aleksandr I Davydov, Olga I Patsap, Elizaveta V Mikhaylenko, Vladimir N Nikolenko, Margarita E Neganova, Sergey G Klochkov, Siva G Somasundaram, Cecil E Kirkland, Gjumrakch Aliev

Open access · hybridAbstract readReview
In one paragraph

Review in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. A Systematic Review of Atypical Endometriosis-Associated Biomarkers.International journal of molecular sciences · 2022
    Pooled it
  3. Pooled it
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  11. Immune pathway through endometriosis to ovarian cancer.World journal of clinical oncology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Liudmila M MikhalevaDepartment of Clinical Pathology, Federal State Budgetary Institution "Research Institute of Human Morphology", 3, Tsyurupy Str, Moscow, 117418, Russian Federation.
Aleksandr I DavydovDepartment of Obstetrics, Gynecology and Perinatology, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2, Trubetskaya Str., Moscow, 119991, Russian Federation.
Olga I PatsapDepartment of Pathology, City Clinical Hospital After Named S.S. Udina, 4, Bld., 3, Kolomensky Passage, Moscow, 115446, Russian Federation.
Elizaveta V MikhaylenkoI. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str, Moscow, 119991, Russia.
Vladimir N NikolenkoI. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str, Moscow, 119991, Russia.
Margarita E NeganovaInstitute of Physiologically Active Compounds, Russian Academy of Sciences, 1 Severny pr, Chernogolovka, Moscow Region, 142432, Russia.
Sergey G KlochkovInstitute of Physiologically Active Compounds, Russian Academy of Sciences, 1 Severny pr, Chernogolovka, Moscow Region, 142432, Russia.
Siva G SomasundaramDepartment of Biological Sciences, Salem University, Salem, WV, 26426, USA.
Cecil E KirklandDepartment of Biological Sciences, Salem University, Salem, WV, 26426, USA.
Gjumrakch AlievDepartment of Clinical Pathology, Federal State Budgetary Institution "Research Institute of Human Morphology", 3, Tsyurupy Str, Moscow, 117418, Russian Federation. cobalt55@gallyinternational.com.ORCID http://orcid.org/0000-0001-7373-3182
Sechenov University · RUInstitute of Physiologically Active Compounds · RUSalem University · USCity Clinical Hospital · RUResearch Institute of Human Morphology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review focuses on pathogenesis of endometriosis, its possible biomarkers and role in endometriosis-associated ovarian cancer. We analyzed various databases to obtain new insights, theories, and biomarkers associated with endometriosis. There are several theories of endometriosis development and biomarker changes including atypical forms. A number of studies have attempted to establish specific, reliable biomarkers to help diagnose endometriosis and endometriosis-associated diseases on the basis of different pathogenetic pathways. Nevertheless, despite intensive research extending even to the molecular level, the origin, natural history, malignant transformation, and laboratory management of endometriosis and related diseases are not yet clearly defined. Therefore, early laboratory diagnoses of endometriosis, its atypical form, and endometriosis-associated ovarian tumors are important problems that require further study in the context of advanced therapeutic strategies to provide maximal health benefits to patients.

Indexed as

Ovarian NeoplasmsAntigens, DifferentiationCell Transformation, NeoplasticEndometriosisFemaleHumansOvarian DiseasesPrognosisAntigens, DifferentiationBiomarkersEndometriosis-associated tumorsEndometriosis pathogenesisPrognosis of endometriosisTreatment of endometriosisWomen’s health

Identifiers

PMID32385745
PMCPMC7467438
OpenAlexW3022148183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.