Evidence map›Paper›PMID 32385686›Full record

ArticleEuropean journal of nutrition2021

The association between antioxidant intake, dietary pattern and depressive symptoms in older Australian men: the Concord Health and Ageing in Men Project.

Arpita Das, Robert G Cumming, Vasi Naganathan, Rosilene V Ribeiro, David G Le Couteur, David J Handelsman, Louise M Waite, Vasant Hirani

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In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Arpita DasSchool of Life and Environmental Science, Charles Perkins Centre, University of Sydney, Sydney, NSW, 2006, Australia. arpita.das@sydney.edu.au.ORCID http://orcid.org/0000-0002-1065-4660
Robert G CummingANZAC Research Institute, University of Sydney and Concord Hospital, Sydney, NSW, Australia.
Vasi NaganathanCentre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, 2139, Australia.
Rosilene V RibeiroSchool of Life and Environmental Science, Charles Perkins Centre, University of Sydney, Sydney, NSW, 2006, Australia.
David G Le CouteurANZAC Research Institute, University of Sydney and Concord Hospital, Sydney, NSW, Australia.
David J HandelsmanANZAC Research Institute, University of Sydney and Concord Hospital, Sydney, NSW, Australia.
Louise M WaiteCentre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, 2139, Australia.
Vasant HiraniSchool of Life and Environmental Science, Charles Perkins Centre, University of Sydney, Sydney, NSW, 2006, Australia.
The University of Sydney · AU

Funding

Ageing and Alzheimers Institute GNT1123014National Health and Medical Research Council 301916Research Council Centre of Excellence in Population Ageing Research Postgraduate Supplementary AwardThe University of Sydney University Postgraduate Award
6 · The paper itself

Abstract

purposeThe objectives of the study were to evaluate the associations between antioxidant intake, dietary patterns and depressive symptoms among older men.

method794 men participated in a detailed diet history interview at the Concord Health and Ageing in Men Project 3rd wave (considered baseline nutrition) and 781 men participated at the 4th wave (considered 3-year follow-up). Depressive symptoms were measured using the Geriatric Depression Scale (GDS ≥ 5). Dietary adequacy of antioxidant intake was assessed by comparing participants' median intake of vitamin A, E, C and zinc to the Nutrient Reference Values for Australia. Attainment of NRVs of antioxidant was categorised into a dichotomised variable 'poor' (meeting ≤ 2) or 'good' (meeting ≥ 3). Individual antioxidant nutrient was categorised into quartiles. The Australian and Mediterranean diet scores were assessed as predictor variables.

resultsThe prevalence of GDS ≥ 5 was 12.8% at baseline nutrition and 13.2% of men developed GDS ≥ 5 at a 3-year follow-up. There was a significant cross-sectional association between poor antioxidant intake and GDS ≥ 5 in adjusted analyses [OR: 1.95 (95% CI 1.03, 3.70)]. Poor antioxidant intake at baseline nutrition remained prospectively associated with incident GDS ≥ 5 [OR: 2.46 (95% CI 1.24, 4.88)] in adjusted analyses. This association was also found for the lowest quartile of zinc [OR 2.72 (95% CI 1.37, 5.42)] and vitamin E intake [OR 2.18 (95% CI 1.05, 4.51)]. None of the other antioxidants and dietary patterns had a significant association with incident depressive symptoms.

conclusionInadequacy of antioxidant intake, particularly zinc and vitamin E, is associated with increased risk of clinically significant depressive symptoms in older men.

Indexed as

AntioxidantsDepressionAgedAgingAustraliaCross-Sectional StudiesDietEatingHumansMaleAntioxidantsDepressive symptomsOlder menVitamin EZinc

Identifiers

PMID32385686
OpenAlexW3022586226

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.