Evidence map›Paper›PMID 32385594›Full record

ArticleInternational journal of legal medicine2020

Skin pigmentation and genetic variants in an admixed Brazilian population of primarily European ancestry.

Jeppe D Andersen, Olivia S Meyer, Filipa Simão, Juliana Jannuzzi, Elizeu Carvalho, Mikkel M Andersen, Vania Pereira, Claus Børsting, Niels Morling, Leonor Gusmão

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of legal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Forensic genetics through the lens of Lewontin: population structure, ancestry and race.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeppe D AndersenSection of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100, Copenhagen, Denmark. jeppe.dyrberg.andersen@sund.ku.dk.ORCID https://orcid.org/0000-0002-4395-5232
Olivia S MeyerSection of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-7842-5581
Filipa SimãoDNA Diagnostic Laboratory (LDD), Institute of Biology, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.
Juliana JannuzziDNA Diagnostic Laboratory (LDD), Institute of Biology, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.
Elizeu CarvalhoDNA Diagnostic Laboratory (LDD), Institute of Biology, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-4620-7253
Mikkel M AndersenDepartment of Mathematical Sciences, Aalborg University, DK-9000, Aalborg, Denmark.ORCID https://orcid.org/0000-0002-0234-0266
Vania PereiraSection of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-8789-5286
Claus BørstingSection of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-0421-7429
Niels MorlingSection of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-9463-5087
Leonor GusmãoDNA Diagnostic Laboratory (LDD), Institute of Biology, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-0432-6481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although many genes have been shown to be associated with human pigmentary traits and forensic prediction assays exist (e.g. HIrisPlex-S), the genetic knowledge about skin colour remains incomplete. The highly admixed Brazilian population is an interesting study population for investigation of the complex genotype-phenotype architecture of human skin colour because of its large variation. Here, we compared variants in 22 pigmentary genes with quantitative skin pigmentation levels on the buttock, arm, and forehead areas of 266 genetically admixed Brazilian individuals. The genetic ancestry of each individual was estimated by typing 46 AIM-InDels. The mean proportion of genetic ancestry was 68.8% European, 20.8% Sub-Saharan African, and 10.4% Native American. A high correlation (adjusted R

Indexed as

Genetic VariationPolymorphism, Single NucleotideBlack PeopleBrazilDNAGenetic MarkersGenotyping TechniquesHumansIndigenous PeoplesSkin PigmentationWhite PeopleDNAGenetic MarkersAdmixed populationAncestryExternally visible characteristicsForensic DNA phenotypingPigmentationSkin colour

Identifiers

PMID32385594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.