Evidence map›Paper›PMID 32385543›Full record

Observational studyThe European journal of health economics : HEPAC : health economics in prevention and care2020

Cost-effectiveness of biennial screening for diabetes related retinopathy in people with type 1 and type 2 diabetes compared to annual screening.

Rebecca L Thomas, Thomas G Winfield, Matthew Prettyjohns, Frank D Dunstan, Wai-Yee Cheung, Philippa M Anderson, Rajesh Peter, Stephen D Luzio, David R Owens

Abstract readObservational Study
In one paragraph

Observational study in The European journal of health economics : HEPAC : health economics in prevention and care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rebecca L ThomasDiabetes Research Unit Cymru, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK. r.l.thomas@swansea.ac.uk.ORCID http://orcid.org/0000-0002-2970-6352
Thomas G WinfieldHealth Technology Wales, 3 Assembly Square, Cardiff, CF10 4PL, UK.
Matthew PrettyjohnsHealth Technology Wales, 3 Assembly Square, Cardiff, CF10 4PL, UK.
Frank D DunstanInstitute of Primary Care and Public Health, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.
Wai-Yee CheungDiabetes Research Unit Cymru, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK.
Philippa M AndersonSwansea Centre for Health Economics, College of Human and Health Sciences, Swansea University, Singleton Park, Swansea, SA2 8PP, UK.
Rajesh PeterSwansea Bay University Health Board, Neath Port Talbot Hospital, Baglan Way, Port Talbot, West Glamorgan, SA12 7BX, UK.
Stephen D LuzioDiabetes Research Unit Cymru, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK.
David R OwensDiabetes Research Unit Cymru, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK.

Funding

National Institute for Social Care and Health Research RFS-12-02
6 · The paper itself

Abstract

objectiveExamine the health and economic impact of extending screening intervals in people with Type 2 diabetes (T2DM) and Type 1 diabetes (T1DM) without diabetes-related retinopathy (DR).

settingDiabetic Eye Screening Wales (DESW). STUDY

designRetrospective observational study with cost-utility analysis (CUA) and Decremental Cost-Effectiveness Ratios (DCER) study.

interventionBiennial screening versus usual care (annual screening). INPUTS: Anonymised data from DESW were linked to primary care data for people with two prior screening events with no DR. Transition probabilities for progression to DR were estimated based on a subset of 26,812 and 1232 people with T2DM and T1DM, respectively. DCER above £20,000 per QALY was considered cost-effective.

resultsThe base case analysis DCER results of £71,243 and £23,446 per QALY for T2DM and T1DM respectively at a 3.5% discount rate and £56,822 and £14,221 respectively when discounted at 1.5%. Diabetes management represented by the mean HbA SENSITIVITY ANALYSIS: Extending screening to biennial based on HbA

conclusionsBase case and sensitivity analyses indicate biennial screening to be cost-effective for T2DM irrespective of HbA

Indexed as

AdultAgedCost-Benefit AnalysisDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic RetinopathyFemaleGlycated HemoglobinHealth ExpendituresHealth ResourcesHumansMaleMarkov ChainsMass ScreeningMiddle AgedModels, EconometricGlycated HemoglobinCost-utility analysisDiabetic retinopathyEconomic impactScreening

Identifiers

PMID32385543
PMCPMC7423794

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.