Evidence map›Paper›PMID 32385384›Full record

ArticleCommunications biology2020

Hydroxy-octadecenoic acids instead of phorbol esters are responsible for the Jatropha curcas kernel cake's toxicity.

Xing-Hong Wang, Jie-Qing Liu, Suiyun Chen, Yanfeng Yin, Yan Liu, Changhe Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Xing-Hong Wang *Yunnan Institute of Microbiology, School of Life Science, Yunnan University, Kunming, 650091, Yunnan, P. R. China.ORCID http://orcid.org/0000-0002-3662-8153
Jie-Qing Liu *School of Biomedical Sciences, Huaqiao University, 362021, Quanzhou, P. R. China.ORCID http://orcid.org/0000-0002-6907-8872
Suiyun Chen *Biocontrol Engineering Research Center of Plant Disease & Pest, Kunming, 650091, Yunnan, P. R. China.ORCID http://orcid.org/0000-0002-0906-5957
Yanfeng YinBiomedical Research Center, Calmette Hospital of Kunming Medical University (Kunming First People's Hospital), Kunming, 650011, Yunnan, P. R. China.
Yan LiuYunnan Institute of Microbiology, School of Life Science, Yunnan University, Kunming, 650091, Yunnan, P. R. China.
Changhe ZhangCenter for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB)/Department of Biology and Environment, Universidade de Trás-os-Montes e Alto Douro (UTAD), Apartado 1013, 5001-801, Vila Real, Portugal. czhang@utad.pt.ORCID http://orcid.org/0000-0002-6502-288X
Yunnan University · CNHuaqiao University · CNKunming Medical University · CNUniversity of Trás-os-Montes and Alto Douro · PTYunnan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxic kernel cake of Jatropha curcas (KCakeJ) is an emerging health and environmental concern. Although phorbol esters are widely recognized as the major toxin of KCakeJ, convincing evidence is absent. Here, we show that rather than phorbol esters an isomeric mixture of 11-hydroxy-9E-octadecenoic acid, 12-hydroxy-10E-octadecenoic acid and 12-hydroxy-10Z-octadecenoic acid (hydroxy-octadecenoic acids, molecular formula C

Indexed as

AnimalsCarpsGoldfishGuinea PigsHumansJatrophaMCF-7 CellsMiceOleic AcidsPhorbol EstersRatsRats, Sprague-DawleySeedsOleic AcidsPhorbol Esters

Identifiers

PMID32385384
PMCPMC7210109
OpenAlexW3022219274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.