SynthesisScientific reports2020
Immunoglobulins as Biomarkers for Gastrointestinal Nematodes Resistance in Small Ruminants: A systematic review.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Complement, coagulation and NET pathway activation underlies early host response to blowfly (Lucilia cuprina) infestation.Parasites & vectors · 2026Article
- Sheep Genetic Resistance to Gastrointestinal Nematode Infections: Current Insights from Transcriptomics and Other OMICs Technologies-A Review.Pathogens (Basel, Switzerland) · 2026Review
- Immunity to helminths in complex environments: co-infection disrupts effective granuloma formation and parasite clearance.Discovery immunology · 2026Article
- A cross-sectional study reveals complex associations between gastrointestinal parasite composition and faecal immune and inflammatory biomarkers in wildlife and livestock in Kenya.Frontiers in immunology · 2026Article
- Article
- Threshold levels of artificial infection with Haemonchus contortus impacting lamb physiology and production.Scientific reports · 2025Article
- Progress in serology and molecular biology of equine parasite diagnosis: sustainable control strategies.Frontiers in veterinary science · 2025Review
- Essential mineral elements in roe deer: Associations with parasites and immune phenotypes in two contrasting populations.Ecology and evolution · 2024Article
- Analysis of Protection and Immune Response againstVaccines · 2024Article
- Understanding Animal-Plant-Parasite Interactions to Improve the Management of Gastrointestinal Nematodes in Grazing Ruminants.Pathogens (Basel, Switzerland) · 2023Review
- Antibody response and abomasal histopathology of lambs with haemonchosis during supplementation with medicinal plants and organic selenium.Veterinary and animal science · 2023Article
- Microbial community in resistant and susceptible Churra sheep infected by Teladorsagia circumcincta.Scientific reports · 2022Article
- The relationship between the intensity of Gasterophilus intestinalis larvae infection and the serum and salivary humoral immune response in horses.Scientific reports · 2022Article
- Status of gastrointestinal nematode infections and associated epidemiological factors in sheep from Córdoba, Colombia.Tropical animal health and production · 2022Article
- Local immune response of Canarian Majorera goats infected with Teladorsagia circumcincta.Parasites & vectors · 2022Article
- Early Transcriptome Differences Between Pre-Infected and Naïve Kid Goats Infected WithFrontiers in veterinary science · 2022Article
- Variants Within GenesFrontiers in genetics · 2022Article
- Teladorsagia Circumcincta Galectin-Mucosal Interactome in Sheep.Veterinary sciences · 2021Article
- In vitro anthelmintic activity ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Genetic Selection for Resistance to Gastrointestinal Parasitism in Meat Goats and Hair Sheep through a Performance Test with Artificial Infection ofAnimals : an open access journal from MDPI · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rise of anthelmintic resistance worldwide has led to the development of alternative control strategies for gastrointestinal nematodes (GIN) infections, which are one of the main constraints on the health of grazing small ruminants. Presently, breeding schemes rely mainly on fecal egg count (FEC) measurements on infected animals which are time-consuming and requires expertise in parasitology. Identifying and understanding the role of immunoglobulins in the mechanisms of resistance could provide a more efficient and sustainable method of identifying nematode-resistant animals for selection. In this study we review the findings on immunoglobulin response to GIN in the literature published to date (june 2019) and discuss the potential to use immunoglobulins as biomarkers. The literature review revealed 41 studies which measured at least one immunoglobulin: 35 focused on lamb immune response (18 used non-naïve lambs) and 7 on yearlings. In this review we propose a conceptual model summarizing the role of immunoglobulins in resistance to GIN. We highlight the need for more carefully designed and documented studies to allow comparisons across different populations on the immunoglobulin response to GIN infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.